Table 2 Demographic, clinical, laboratory and radiological characteristics of 33 hospitalized young adults with COViD-19 considered in this study
Characteristics | No ICU care (n = 27) | ICU care (n = 6) | p value |
|---|---|---|---|
Mean age ± SD – years | 45.48 ± 5.09 | 42.5 ± 8.26 | 0.257 |
Male gender – no. (%) | 16 (59.3%) | 3 (50%) | > 0.999 |
Healthcare worker – no. (%) | 2 (7.4% | 0 | > 0.999 |
Mean BMI ± SD | 28.7 ± 4.8 | 28.6 ± 2.84 | 0.989 |
Smoking habit – no. (%) | 1 (4%) | 1 (33.3%) | 0.206 |
Coexisting conditions | |||
Hypertension | 3 (11%) | 0 | > 0.999 |
Diabetes | 2 (7.4%) | 0 | > 0.999 |
Chronic liver disease | 1 (3.7%) | 0 | > 0.999 |
Neurological disease and mental disorder | 1 (3.7%) | 3 (50%) | 0.014 |
Thyroid diseases | 0 | 1 (16.7%) | 0.182 |
Signs and symptoms at the onset | |||
Fever | 100% | 100% | – |
Cough | 21 (77.8%) | 2 (33.3%) | 0.053 |
Dyspnoea | 13 (48.1%) | 4 (66.7%) | 0.656 |
Chest pain | 6 (22.2%) | 0 | 0.563 |
Fatigue | 5 (18.5%) | 0 | 0.556 |
Anosmia | 3 (11.1%) | 0 | > 0.999 |
Diarrhoea | 6 (22.2%) | 1 (16.7%) | > 0.999 |
Vomiting | 1 (3.7%) | 0 | > 0.999 |
Headache | 1 (3.7%) | 1 (16.7%) | 0.335 |
Myalgia | 4 (14.8%) | 0 | > 0.999 |
Syncope | 6 (22.2%) | 1 (16.7%) | 0.335 |
Respiratory distress syndrome | 6 (22.2%) | 6 (100%) | 0.001 |
Vital signs | |||
Systolic blood pressure. mm Hg | 132 ± 18.1 | 131 ± 20 | 0.895 |
Heart rate | 93.3 ± 16.3 | 103 ± 3.51 | 0.291 |
Laboratory findings | |||
White blood cell count, ×109/L (normal range 4–11) | 6.437 ± 2.981 | 5.511 ± 2.714 | 0.492 |
Lymphocyte count, ×109/L (normal range 1–4) | 1.091 ± 0.460 | 1.183 ± 1.051 | 0.739 |
Platelet count, × 109/L (normal range 150–400) | 199(144.750–260.500) | 156.5 (138.750–181.750) | 0.308 |
Alanine aminotransferase, U/L (normal range 0–35) | 39 (30.2–52) | 25 (17.5–28.7) | 0.055 |
Aspartate aminotransferase, U/L (normal range 0–35) | 43 (28.5–49.7) | 35 (30.7–67) | 0.906 |
Creatinine, mg/dl (normal range 0.67–1.17) | 0.86 ± 0.218 | 1 ± 0.294 | 0.093 |
Potassium, mEq/L (normal range 3.5–5.1) | 4.1 ± 0.332 | 3.7 ± 0.460 | 0.028 |
Lactate dehydrogenase, U/L (normal range 0–247) | 297 (255–365) | 483 (362–729) | 0.141 |
C-reactive protein mg/mL (normal range 0–0.49) | 6.5 (2.55–11.25) | 11.7 (11.1–14.1) | 0.097 |
Involvement on chest radiographs | |||
No involvement | 1 (3.7%) | 0 (0%) | 0.865 |
Ground-glass opacity | 4 (14.8%) | 1 (16.7%) | |
Bilateral lung patch shadow | 20 (74.1%) | 5 (83.3%) | |
Focal lesions | 2 (7.4%) | 0 (0%) | |