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Table 1 Demographic, clinical, laboratory and radiological characteristics of 104 young adults with COViD-19 considered in this study

From: Clinical characteristics, management and health related quality of life in young to middle age adults with COVID-19

Characteristics

All patients (n = 104)

Outpatients (n = 71)

Inpatients (n = 33)

p value

Mean age ± SD – years

41.1 ± 7.4

39.5 ± 7.5

44.8 ± 5.8

< 0.001

Male gender – no. (%)

56 (53.8%)

37 (52.1%)

19 (57.6%)

0.757

Healthcare worker – no. (%)

13 (12.5%)

11 (15.5%)

2 (6.1%)

0.218

Mean BMI (Body mass index) ± SD

27.1 ± 5.01

26.37 ± 5.12

28.6 ± 4.46

0.029

Smoking habit – no. (%)

11 (10.6%)

9 (13.8%)

2 (7.1%)

0.495

Coexisting conditions

 Hypertension

11 (10.6%)

8 (11.3%)

3 (9.1%)

> 0.999

 Diabetes

4 (3.8%)

2 (2.8%)

2 (6.1%)

0.590

 Chronic obstructive pulmonary disease

2 (1.9%)

2 (2.8%)

0

> 0.999

 Cerebrovascular disease

1 (1%)

1 (1.4%)

0

> 0.999

 Chronic liver disease

3 (2.9%)

2 (2.8%)

1 (3%)

> 0.999

 Neurological disease and mental disorder

6 (5.8%)

2 (2.8%)

4 (12.1%)

0.079

 Malignancy

3 (2.9%)

3 (4.2%)

0

0.550

 Thyroid diseases

8 (7.7%)

7 (9.9%)

1 (3%)

0.431

Days from illness onset to visit hospital

8.8 ± 6.05

8.5 ± 6.49

8.5 ± 6.07

0.996

Signs and symptoms at the onset

 Fever

94 (90.4%)

61 (85.9%)

33 (100%)

0.028

 Cough

58 (55.8%)

35 (49.3%)

23 (69.7%)

0.082

 Dyspnoea

35 (33.7%)

18 (25.4%)

17 (51.5%)

0.016

 Chest pain

15 (14.4%)

9 (12.7%)

6 (18.2%)

0.551

 Fatigue

18 (17.3%)

13 (18.3%)

5 (15.2%)

0.906

 Sore throat

9 (8.7%)

9 (12.7%)

0

0.054

 Anosmia

17 (16.3%)

14 (19.7%)

3 (9.1%)

0.280

 Diarrhoea

16 (15.4%)

9 (12.7%)

7 (21.2%)

0.406

 Vomiting

5 (4.8%)

4 (5.6%)

1 (3%)

> 0.999

 Headache

8 (7.7%)

6 (8.5%)

2 (6.1%)

> 0.999

 Myalgia

11 (10.6%)

7 (9.9%)

4 (12.1%)

0.740

 Syncope

6 (5.8%)

4 (5.6%)

2 (6.1%)

> 0.999

Respiratory distress syndrome

14 (13.95%)

2 (2.8%)

12 (36.4%)

< 0.001

Vital signs

 Systolic blood pressure. mm Hg

96 ± 15.51

128 ± 14

132 ± 18.1

0.289

 Heart rate

91.7 ± 17.45

90.3 ± 18.3

94.6 ± 15.6

0.329

 Respiratory rate

18 (17–24)

17 (16–18)

18 (17–24)

0.171

Laboratory findings

 White blood cell count, × 109/L (normal range 4–11)

5.820 ± 2.489

5.614 ± 2.259

6.264 ± 2.913

0.224

 Lymphocyte count, ×109/L (normal range 1–4)

1.318 ± 0.609

1.415 ± 0.597

1.109 ± 0.592

0.018

 Platelet count, ×109/L (normal range 150–400)

186 (152–248)

183 (161–246)

190.5 (142–250)

0.693

 Alanine aminotransferase, U/L (normal range 0–35)

28 (18–40)

21 (15–33)

36.2 (26.7–50)

0.001

 Aspartate aminotransferase, U/L (normal range 0–35)

24 (42–20.5)

24 (19–30)

42 (29.7–51)

< 0.001

 Creatinine, mg/dl (normal range 0.67–1.17)

0.844 ± 0.21

0.823 ± 0.19

0.890 ± 0.24

0.128

 Potassium, mEq/L (normal range 3.5–5.1)

3.99 ± 0.36

3.96 ± 0.348

4.05 ± 0.38

0.248

 Lactate dehydrogenase, U/L (normal range 0–247)

250.5 (176.5–326.5)

179 (150–221)

317 (259–448)

< 0.001

 Creatine kinase, U/L (normal range 0–195)

73 (49.25–124.5)

67.5 (49–90.7)

116 (59–270)

0.034

 Procalcitonin ng/mL (normal range 0.38)

0.03 (0.02–0.08)

0.02 (0.02–0.04)

0.07 (0.02–0.132)

0.018

 C-reactive protein mg/mL (normal range 0–0.49)

1.74 (0.49–5.72)

0.89 (0.195–2.44)

7.63 (2.66–11.72)

< 0.001

 D-dimer, ng/L (normal range 0–500)

587 (298–920)

406 (263–494)

861 (591–1165)

0.001

Involvement on chest radiographs

 No involvement

27 (26%)

26 (37.7%)

1 (3%)

< 0.001

 Ground-glass opacity

28 (26.9%)

23 (33.3%)

5 (15.2%)

 Bilateral lung patch shadow

37 (35.6%)

12 (17.4%)

25 (75.8%)

 Focal lesions

10 (9.6%)

8 (11.6%)

2 (6.1%)

  1. Data are expressed as mean ± SD, median (IQR) or n (%)
  2. p values indicate differences between out and in-patients. P < .05 was considered statistically significant
  3. In brackets are expressed percentages and IQR