Fig. 1

Laboratory Trends According to Days of Illness. WBC: white blood cell, NLR: neutrophil to lymphocyte ratio, CRP: C-reactive protein, LDH: lactic acid dehydrogenase. Locally weighted scatterplot smoothing (LOWESS) curves showing the associations of WBC, CRP, NLR, and D-dimer with days of illness in critically ill COVID-19 patients. The shaded area represents the 95% confidence intervals. Each patients’ laboratory tests were obtained on the day of admission but are plotted according to the day of illness