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Table 4 Complications, treatment pattern and clinical outcomes of included patients

From: Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province

  Diagnosis Disease severity
  Suspected
(n = 22)
Laboratory-confirmed
(n = 147)
Non-severe
(n = 122)
Severe
(n = 25)
P value#
Complications
Any Complications 2/19 (10·5) 15/146 (10·3) 3/122 (2·5) 12/24 (50·0) <  0·0001
  Respiratory failure 1/19 (5·3) 9/146 (6·2) 2/122 (1·6) 7/24 (29·2) <  0·0001
  Secondary bacterial pneumonia 0/19 (0·0) 4/146 (2·7) 0/122 (0·0) 4/24 (16·7) >  0·99*
  Coagulation disorders 0/19 (0·0) 2/146 (1·4) 0/122 (0·0) 2/24 (8·3) 0·03*
  Metabolic acidosis 0/19 (0·0) 1/146 (0·7) 0/122 (0·0) 1/24 (4·2) 0·16*
  Shock 0/19 (0·0) 1/146 (0·7) 0/122 (0·0) 1/24 (4·2) 0·16*
  Bacteremia or Sepsis 1/19 (5·3) 2/146 (1·4) 0/122 (0·0) 2/24 (8·3) 0·026*
  Acute lung injury or ARDS 0/19 (0·0) 1/146 (0·7) 0/122 (0·0) 1/24 (4·2) 0·16*
  Acute renal injury 0/19 (0·0) 0/146 (0·0) 0/122 (0·0) 0/24 (0·0) ··
Treatment
Antiviral treatment 11/14 (78·6) 144/146 (98·6) 119/121 (98·3) 25/25 (100·0) >  0·99*
  Ribavirin 3/14 (21·4) 14/146 (9·6) 10/121 (8·3) 4/25 (16·0) 0·23
  Interferon 8/14 (57·1) 95/146 (65·1) 77/121 (63·6) 18/25 (72·0) 0·43
  Lopinavir/Litonavir 4/14 (28·6) 133/146 (91·1) 114/121 (94·2) 19/25 (76·0) 0·0040
  Oseltamivir 4/14 (28·6) 22/146 (15·1) 17/121 (14·1) 5/25 (20·0) 0·45
Antibiotic treatment 9/16 (56·3) 81/144 (56·3) 59/120 (49·2) 22/24 (91·7) <  0·0001
Glucocorticoids 1/15 (6·7) 34/126 (27·0) 16/101 (15·8) 18/25 (72·0) <  0·0001
Intravenous immunoglobulin therapy 1/22 (4·5) 8/147 (5·4) 4/122 (3·3) 4/25 (16·0) 0·010
Oxygen therapy 7/22 (31·8) 59/147 (40·1) 41/122 (33·6) 18/25 (72·0) <  0·0001
Mechanical ventilation (MV) 2/22 (9·1) 12/147 (8·2) 0/122 (0·0) 12/25 (48·0) <  0·0001
  Non-invasive MV 2/22 (9·1) 11/147 (7·5) 0/122 (0·0) 11/25 (44·0) <  0·0001
  Invasive MV 1/22 (4·5) 2/147 (1·4) 0/122 (0·0) 2/25 (8·0) 0·029*
ECMO 0/22 (0·0) 0/147 (0·0) 0/122 (0·0) 0/25 (0·0) ··
CRRT 0/22 (0·0) 1/147 (0·7) 0/122 (0·0) 1/25 (4·0) 0·17*
Clinical outcomes
ICU admission 0/22 (0·0) 4/147 (2·7) 0/122 (0·0) 4/25 (16·0) 0.00068
Death 0/22 (0·0) 0/147 (0·0) 0/122 (0·0) 0/25 (0·0) ··
  1. Values are No./total No. (%)
  2. Abbreviations: ICU Intensive Care Units, ECOM Extracorporeal Membrane Oxygenation, CRRT Continuous Renal Replacement Therapy, ARDS Acute Respiratory Distress Syndrome
  3. * The P-value was derived from Fisher’s exact test, two-sided
  4. # P-value for the comparison between severe cases versus non- severe infected patients
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