Table 2 Symptoms and Signs of included patients
From: Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province
Diagnosis | Disease severity | ||||
|---|---|---|---|---|---|
Suspected (n = 22) | Laboratory-confirmed (n = 147) | Non-severe (n = 122) | Severe (n = 25) | P value# | |
Symptoms | |||||
Fever from onset to admission, No./total (%) | 16/21 (76·2) | 98/139 (70·5) | 78/116 (67·2) | 20/23 (87·0) | 0·10 |
Highest temperature from onset to admission, median (IQR), °C | 38·1 (37·8–38·5) | 38·0 (37·4–38·5) | 37·8 (37·2–38·5) | 38·5 (38–38·8) | 0·0040 |
< 37·5 | 6/19 (31·6) | 32/101 (31·7) | 30/83 (36·1) | 2/18 (11·1) | 0·076* |
37·5–38·0 | 4/19 (21·1) | 32/101 (31·7) | 25/83 (30·1) | 7/18 (38·9) | ·· |
38·1–39·0 | 8/19 (42·1) | 33/101 (32·7) | 26/83 (31·3) | 7/18 (38·9) | ·· |
> 39·0 | 1/19 (5·3) | 4/101 (4·0) | 2/83 (2·4) | 2/18 (11·1) | ·· |
Fever throughout the course of disease, No./total (%) | 18/22 (81·8) | 119/147 (81·0) | 96/122 (78·7) | 23/25 (92·0) | 0·21 |
Highest temperature throughout the course of disease, median IQR), °C | 38·3 (37·7–38·5) | 38·0 (37·4–38·7) | 38·0 (37·3–38·5) | 38·5 (38–38·8) | 0·0080 |
< 37·5 | 5/20 (25·0) | 34/131 (26·0) | 32/108 (29·6) | 2/23 (8·7) | 0·025* |
37·5–38·0 | 2/20 (20·0) | 32/131 (24·4) | 27/108 (25·0) | 5/23 (21·7) | ·· |
38·1–39·0 | 11/20 (55·0) | 57/131 (43·5) | 45/108 (41·7) | 12/23 (52·2) | ·· |
> 39·0 | 2/20 (20·0) | 8/131 (6·1) | 4/108 (3·7) | 4/23 (17·4) | ·· |
Respiratory symptoms from onset to admission, No./total (%) | 20/22 (90·9) | 118/147 (80·3) | 95/122 (77·9) | 23/25 (92·0) | 0·18 |
Cough | 19/22 (86·4) | 104/147 (70·7) | 81/122 (66·4) | 23/25 (92·0) | 0·020 |
Sputum | 10/22 (45·5) | 49/147 (33·3) | 34/122 (27·9) | 15/25 (60·0) | 0·0040 |
Shortness of breath | 5/22 (22·7) | 20/147 (13·6) | 10/122 (8·2) | 10/25 (40·0) | < 0·0001 |
Respiratory symptoms throughout the course of disease, No./total (%) | 21/22 (95·5) | 129/147 (87·8) | 105/122 (86·1) | 24/25 (96·0) | 0·30 |
Cough | 20/22 (90·9) | 118/147 (80·3) | 95/122 (77·9) | 23/25 (92·0) | 0·18 |
Sputum production | 12/22 (54·5) | 76/147 (51·7) | 59/122 (48·4) | 17/25 (68·0) | 0·12 |
Shortness of breath | 7/22 (31·8) | 33/147 (22·4) | 19/122 (15·6) | 14/25 (56·0) | < 0·0001 |
Gastrointestinal symptoms from onset to admission, No./total (%) | 1/22 (4·5) | 17/147 (11·6) | 15/122 (12·3) | 2/25 (8·0) | 0·79 |
Diarrhea | 1/22 (4·5) | 15/147 (10·2) | 14/122 (11·5) | 1/25 (4·0) | 0·45 |
Gastrointestinal symptoms throughout the course of disease, No./total (%) | 2/22 (9·1) | 54/147 (36·7) | 49/122 (40·2) | 5/25 (20·0) | 0·093 |
Diarrhea | 2/22 (9·1) | 43/147 (29·3) | 40/122 (32·8) | 3/25 (12·0) | 0·066 |
Other symptoms from onset to admission, No./total (%) | 6/22 (27·3) | 59/147 (40·1) | 48/122 (39·3) | 11/25 (44·0) | 0·84 |
Fatigue | 4/22 (18·2) | 32/147 (21·8) | 27/122 (22·1) | 5/25 (20·0) | > 0·99* |
Chill | 1/22 (4·5) | 17/147 (11·6) | 12/122 (9·8) | 5/25 (20·0) | 0·27 |
Other symptoms throughout the course of disease, No./total (%) | 6/22 (27·3) | 74/147 (50·3) | 57/122 (46·7) | 17/25 (68·0) | 0·086 |
Fatigue | 4/22 (18·2) | 42/147 (28·6) | 34/122 (27·9) | 8/25 (32·0) | 0·86 |
Chill | 1/22 (4·5) | 22/147 (15) | 15/122 (12·3) | 7/25 (28·0) | 0·090 |
Signs | |||||
Respiratory rate at admission, median (IQR) | 20 (19–21) | 20 (20–21) | 20 (20–20) | 21 (20–22) | 0·0020 |
SBP at admission, median (IQR), mmHg | 127 (117–135) | 126 (116–139) | 126 (116–138) | 128 (119–139) | 0·38 |
> 140 mmHg, No·/total (%) | 4/17 (23·5) | 26/129 (20·2) | 21/108 (29·4) | 5/21 (23·8) | 0·87 |
DBP at admission, median (IQR), mmHg | 80 (74–86) | 79 (72–88) | 79 (71–88) | 80 (75–86) | 0·94 |
> 90 mmHg, No·/total (%) | 3/17 (17·6) | 28/129 (21·7) | 24/108 (22·2) | 4/21 (19·0) | 0·97 |
Heart rate at admission, median (IQR) | 90 (80–106) | 90 (80–103) | 90 (80–99) | 104 (91–109) | 0·0050 |