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Table 2 Symptoms and Signs of included patients

From: Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province

  Diagnosis Disease severity
Suspected
(n = 22)
Laboratory-confirmed
(n = 147)
Non-severe
(n = 122)
Severe
(n = 25)
P value#
Symptoms
Fever from onset to admission, No./total (%) 16/21 (76·2) 98/139 (70·5) 78/116 (67·2) 20/23 (87·0) 0·10
Highest temperature from onset to admission, median (IQR), °C 38·1 (37·8–38·5) 38·0 (37·4–38·5) 37·8 (37·2–38·5) 38·5 (38–38·8) 0·0040
 < 37·5 6/19 (31·6) 32/101 (31·7) 30/83 (36·1) 2/18 (11·1) 0·076*
 37·5–38·0 4/19 (21·1) 32/101 (31·7) 25/83 (30·1) 7/18 (38·9) ··
 38·1–39·0 8/19 (42·1) 33/101 (32·7) 26/83 (31·3) 7/18 (38·9) ··
 > 39·0 1/19 (5·3) 4/101 (4·0) 2/83 (2·4) 2/18 (11·1) ··
Fever throughout the course of disease, No./total (%) 18/22 (81·8) 119/147 (81·0) 96/122 (78·7) 23/25 (92·0) 0·21
Highest temperature throughout the course of disease, median IQR), °C 38·3 (37·7–38·5) 38·0 (37·4–38·7) 38·0 (37·3–38·5) 38·5 (38–38·8) 0·0080
 < 37·5 5/20 (25·0) 34/131 (26·0) 32/108 (29·6) 2/23 (8·7) 0·025*
 37·5–38·0 2/20 (20·0) 32/131 (24·4) 27/108 (25·0) 5/23 (21·7) ··
 38·1–39·0 11/20 (55·0) 57/131 (43·5) 45/108 (41·7) 12/23 (52·2) ··
 > 39·0 2/20 (20·0) 8/131 (6·1) 4/108 (3·7) 4/23 (17·4) ··
Respiratory symptoms from onset to admission, No./total (%) 20/22 (90·9) 118/147 (80·3) 95/122 (77·9) 23/25 (92·0) 0·18
 Cough 19/22 (86·4) 104/147 (70·7) 81/122 (66·4) 23/25 (92·0) 0·020
 Sputum 10/22 (45·5) 49/147 (33·3) 34/122 (27·9) 15/25 (60·0) 0·0040
 Shortness of breath 5/22 (22·7) 20/147 (13·6) 10/122 (8·2) 10/25 (40·0) <  0·0001
Respiratory symptoms throughout the course of disease, No./total (%) 21/22 (95·5) 129/147 (87·8) 105/122 (86·1) 24/25 (96·0) 0·30
 Cough 20/22 (90·9) 118/147 (80·3) 95/122 (77·9) 23/25 (92·0) 0·18
 Sputum production 12/22 (54·5) 76/147 (51·7) 59/122 (48·4) 17/25 (68·0) 0·12
 Shortness of breath 7/22 (31·8) 33/147 (22·4) 19/122 (15·6) 14/25 (56·0) <  0·0001
Gastrointestinal symptoms from onset to admission, No./total (%) 1/22 (4·5) 17/147 (11·6) 15/122 (12·3) 2/25 (8·0) 0·79
 Diarrhea 1/22 (4·5) 15/147 (10·2) 14/122 (11·5) 1/25 (4·0) 0·45
Gastrointestinal symptoms throughout the course of disease, No./total (%) 2/22 (9·1) 54/147 (36·7) 49/122 (40·2) 5/25 (20·0) 0·093
 Diarrhea 2/22 (9·1) 43/147 (29·3) 40/122 (32·8) 3/25 (12·0) 0·066
Other symptoms from onset to admission, No./total (%) 6/22 (27·3) 59/147 (40·1) 48/122 (39·3) 11/25 (44·0) 0·84
 Fatigue 4/22 (18·2) 32/147 (21·8) 27/122 (22·1) 5/25 (20·0) >  0·99*
 Chill 1/22 (4·5) 17/147 (11·6) 12/122 (9·8) 5/25 (20·0) 0·27
Other symptoms throughout the course of disease, No./total (%) 6/22 (27·3) 74/147 (50·3) 57/122 (46·7) 17/25 (68·0) 0·086
 Fatigue 4/22 (18·2) 42/147 (28·6) 34/122 (27·9) 8/25 (32·0) 0·86
 Chill 1/22 (4·5) 22/147 (15) 15/122 (12·3) 7/25 (28·0) 0·090
Signs
Respiratory rate at admission, median (IQR) 20 (19–21) 20 (20–21) 20 (20–20) 21 (20–22) 0·0020
SBP at admission, median (IQR), mmHg 127 (117–135) 126 (116–139) 126 (116–138) 128 (119–139) 0·38
 > 140 mmHg, No·/total (%) 4/17 (23·5) 26/129 (20·2) 21/108 (29·4) 5/21 (23·8) 0·87
DBP at admission, median (IQR), mmHg 80 (74–86) 79 (72–88) 79 (71–88) 80 (75–86) 0·94
 > 90 mmHg, No·/total (%) 3/17 (17·6) 28/129 (21·7) 24/108 (22·2) 4/21 (19·0) 0·97
Heart rate at admission, median (IQR) 90 (80–106) 90 (80–103) 90 (80–99) 104 (91–109) 0·0050
  1. Abbreviations: IQR Interquartile range, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure
  2. * The P-value was derived from Fisher’s exact test, two-sided
  3. # P-value for the comparison between severe cases versus non- severe infected patients
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