Molecular characterization of the viral structural protein genes in the first outbreak of dengue virus type 2 in Hunan Province, inland China in 2018

Table 1 Selection pressure analysis of the structural protein of DENV-2 (n = 202) using FEL, IFEL, MEME, and FUBAR

Serial number	AA position	FEL		IFEL		MEME		FUBAR
Serial number	AA position	ω	p-Value	ω	p-Value	ω	p-Value	ω	Posterior Prob(α<β)
1	11	/	/	/	/	>100	0.083	/	/
2	19	/	/	/	/	>100	0.027	/	/
3	35	/	/	/	/	>100	0.066	0.132	0.963
4	207	/	/	/	/	>100	0.061	0.174	0.916
5	209	0.049	0.000	0.114	0.012	>100	0.078	0.068	1.000
6	228	/	/	/	/	>100	0.056	/	/
7	332	/	/	/	/	>100	0.032	/	/
8	400	/	/	/	/	>100	0.004	/	/
9	451	0.070	0.014	0.000	0.011	>100	0.069	0.082	0.998
10	463	/	/	/	/	>100	0.037	/	/
11	464	0.164	0.008	0.000	0.001	>100	0.000	0.182	0.988
12	474	/	/	/	/	>100	0.089	/	/
13	475	0.153	0.078	0.000	0.047	>100	0.053	0.130	0.983
14	488	/	/	/	/	>100	0.053	0.164	0.928
15	506	/	/	/	/	>100	0.052	/	/
16	521	/	/	/	/	>100	0.053	0.133	0.976

Note: Criteria to consider sites with significant evidence of positive selection: p-value < 0.1 in FEL, IFEL, and MEME, Posterior Prob (α < β) > 0.9 in FUBAR, and omega should be greater than 1. Sites that were found to be positive by at least one method are included in the list. “/”: represents that the site was not selected by the corresponding method as a positive or negative selection. “AA”: represents amino acids

ISSN: 1471-2334