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Table 1 Description of NSEBA study sites in Southern Province, Zambia, 2016–2018

From: Point-of-care p24 antigen detection for early infant diagnosis of HIV infection: cross-sectional and longitudinal studies in Zambia

Study site Area Type of area Study period
(mm/yy)
Median (range) deliveries per week by women living with HIV Median (range) DBS collected per week for EID Eligible participants Timing of follow-up Staff trained to perform LYNX assay
Livingstone Central Hospital Livingstone City Urban 06/16–05/17
06/17–04/18
8 (1, 15) N/A All HEI
High-risk HEIa
Birth only 1 Research staffc
Maramba UHC Livingstone City Urban 06/16–05/17
06/17–04/18
3 (0, 12) N/A All HEI
High-risk HEIa
Birth only 1 Research staffc
Mahatma Gandhi UHC Livingstone City Urban 04/17–04/18 3 (0, 9) N/A High-risk HEIa Birth only 1 Research staffc
Libuyu UHC Livingstone City Urban 04/17–04/18 1 (0, 5) N/A High-risk HEIa Birth only 1 Research staffc
Choma General Hospital Choma City Urban 08/17–04/18 5 (2, 9) N/A High-risk HEIa Birth only 2 Nurses
Shampande UHC Choma City Urban 08/17–04/18 2 (0, 5) N/A High-risk HEIa Birth only 2 Nurses
Macha Hospital Macha area Rural 04/16–09/18 2 (0, 9) 3 (0, 11) All HEI Testing periodb 5 Counselors
6 Research staffc
Mapanza RHC Macha area Rural 04/16–09/18 0 (0, 4) 1 (0, 7) All HEI Testing periodb 1 Clinical Officer
2 Nurses
1 Counselor
Moboola RHC Macha area Rural 04/16–09/18 0 (0, 3) 1 (0, 7) All HEI Testing periodb 2 Nurses
1 Counselor
Mangunza RHC Macha area Rural 04/16–09/18 0 (0, 3) 1 (0, 5) All HEI Testing periodb 1 Nurse
1 Counselor
Nalube RHC Macha area Rural 04/16–07/17 0 (0, 2) 0 (0, 3) All HEI Testing periodb 1 Nurse
1 Counselor
  1. DBS Dried blood spots, EID Early infant diagnosis, HEI HIV-exposed infants, N/A Not applicable, RHC Rural health clinic, UHC Urban health center
  2. a High-risk defined as mothers receiving no antiretroviral drugs throughout pregnancy or starting to receive antiretroviral drugs during pregnancy to prevent mother-to-child transmission
  3. b Testing period includes any point of contact for early infant diagnosis testing from birth to post-weaning (e.g. birth, 6 weeks, 6 months, 12 months, 18 months, 24 months, post-weaning)
  4. c Research staff in Livingstone included 3 nurses; research staff in Macha included 1 nurse, 1 laboratory scientist, and 4 counselors by training