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Table 1 Paediatric patients admitted with COVID-19

From: A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

Age

Range (years)

Sex

Past medical history

Clinical presentation

Laboratory findings

Infiltrates in X-ray or CT

Treatment

Co-Infections

Complications b)

MIS-C

Outcome

Fever

Respiratory Symptoms

Gastrointestinal Symptoms

Other

Symptoms

Max. CRP (mg/dl)

Max. D-Dimer (μg/ml)

Max. Troponin (ng/ml)

PICU treatment

Oxygen support

Invasive ventilation

Pharmaco-logical treatment b)

1

< 1

m

Healthy

X

 

X

 

Neg

NA

NA

NA

    

None

None

 

Complete recovery

2

≥ 16

w

Kidney transplantation 2008, immunosuppressive treatment

X

X

X

 

38

50

507

Yes

X

X

X

Antibiotic, antifungal, heparin

None

Pneumonia, pleural effusion, acute renal failure, hypertension

X

Complete recovery

3

≥ 16

m

Hypoplastic left heart syndrome

 

X

 

Hypoxaemia

15

6

Neg

No

X

X

 

None

None

Cerebral vasculitis, myocarditis

X

Died 11 days after discharge

4

6–12

m

Oesophageal atresia, recurrent otitis media, multiple interventions

X

 

X

Orbital swelling

16

5

Neg

NA

   

Antibiotic

NA

None

 

Mild residual symptoms

5 = 15

6–12

m

Rhabdomyosarcoma, cytotoxic chemotherapy

 

X

  

5

Neg

Neg

NA

   

Antibiotic

None

None

 

Complete recovery, Reinfection

6

6–12

w

Healthy

X

X

X

 

16

5

14

Yes

 

X

 

Antibiotic, heparin, defibrotide

None

Terminal ileitis, pneumonia, polyserositis

X

Complete recovery

7

≥ 16

w

Severe immunodeficiency syndrome with T-cell-disorder, HSCT 2019

X

X

X

 

14

1

Neg

Yes

 

X

 

Antibiotic, antifungal, ribavirin, valganciclovir

Throat swab: HSV-1, CMV, EBV, HHV-6, Enterobacter cloacae

Pneumonia, pericardial effusion

X

Complete recovery

8

< 1

w

Healthy

   

Livid discoloration of the legs

2

2

NA

NA

   

None

NA

None

 

Mild residual symptoms

9

6–12

w

Asthma, obesity

X

X

  

Neg

Neg

Neg

NA

   

Inhaled beta-2-mimetics

NA

None

 

Complete recovery

10

13–15

m

Sickle cell anaemia, Asthma

 

X

 

Haematuria

6

7

Neg

No

 

Xa)

 

Antibiotic, heparin

NA

None

 

Mild residual symptoms

11

13–15

m

Healthy

X

X

X

Haemat-emesis

13

1

Neg

Yes

   

Antibiotic, heparin

Sputum: Streptococcus pneumoniae

Bacterial pneumonia

 

Mild residual symptoms

12

< 1

m

Healthy

X

X

  

Neg

NA

NA

NA

   

Antibiotic

None

None

 

complete recovery

13

1–2

w

Chronic Bronchitis

X

X

  

2,5

Neg

Neg

NA

   

None

NA

None

 

complete recovery

14

≥ 16

w

Liver transplantation 2019, immunosuppressive treatment

 

X

X

 

6

NA

NA

NA

   

None

NA

None

 

complete recovery

15 = 5

6–12

m

Rhabdomyosarcoma, cytotoxic chemotherapy

 

X

  

Neg

Neg

Neg

NA

   

None

NA

None

 

Mild residual symptoms

  1. Abbreviations: CMV cytomegalovirus, CRP C-reactive protein, CT computed tomography, EBV Epstein-Barr virus, F female, HHV-6 human herpesvirus 6, HSCT haematopoietic stem cell transplantation, HSV herpes simplex virus, M male, MIS-C multisystem inflammatory syndrome in children, neg negative, NA not assessed, PICU paediatric intensive care unit
  2. aTherapeutic oxygen without respiratory impairment; bCOVID-19 related