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Table 2 Blood parameters and microbiological data

From: The different manifestations of COVID-19 in adults and children: a cohort study in an intensive care unit

  Total
n = 20
Adults
n = 16
Children
n = 4
p-value
Biomarkers
 Mid-regional pro-adrenomedullin (nmol/L) 0.85 (0.65–1.15) 0.78 (0.64–0.88) 1.72 (1.55–2.77) 0.017
 Procalcitonin (ng/mL) 0.22 (0.12–0.48) 0.19 (0.11–0.37) 5.7 (1.3–7.77) 0.023
 C-reactive protein (mg/L) 181.5 (62.5–237.7) 146.95 (57.58–192.98) 328.2 (252.8–351.15) 0.005
 Troponines (ng/mL) 0.004 (0.002–0.035) 0.003 (0.002–0.014) 0.09 (0.01–2.85) 0.039
 NT-proBNP 2414 (59–4840) 59 (55.5–375) 4057 (2629–18,211) 0.034
Blood samples
 Lymphocytes (/mm3) 1000 (700–1175) 1000 (700–1100) 1100 (475–8175) 0.703
 Prothrombin time (%) 84.5 (65.6–94.8) 88 (83.3–96.8) 56.4 (47.5–63.6) 0.006
 Triglycerides (mg/dL) 391 (180.5–603.5) 413 (255–623) 158 (116–167) 0.015
 D-dimer, at admission (mg/L) 2.45 (1.1–5) 2.45 (0.82–4.46) 3.94 (1.35–7) 0.571
 D-dimer, maximum (mg/L) 6.3 (2.1–8.6) 5.45 (1.89–9.98) 6.75 (5.63–8.33) 0.539
 Ferritin, maximum (ug/L) 910 (359.7–3614.5) 999.5 (311.1–4210.5) 714.8 (567–1369.25) 0.637
 Lactate dehydrogenase, maximum (IU/L) 838 (760–1464) 1053.5 (711–1616) 800 (791–819) 0.576
 IL-6, maximum (pg/mL) 460.5 (52.5–1000) 709.5 (24.7–1000) 141.75 (61.1–804.75) 0.829
Microbiological data
 Healthcare-associated infection, n (%) 8 (40) 8 (50) 0 (0) 0.103
 CLABSI, n (%) 7 (35) 7 (43.8)   
  - S. epidermidis 5 (71.4) 5 (71.4)   
  - K. pneumoniae 1 (14.3) 1 (14.3)   
  - C. albicans 1 (14.3) 1 (14.3)   
 CAUTI, n (%) 5 (25) 5 (31.3)   
  - P. aeruginosa 2 (40) 2 (40)   
  - K. pneumoniae 1 (10) 1 (10)   
  - E. coli 2 (40) 2 (40)   
 VAP, n (%) 2 (10) 2 (40)   
  - R. ornithinolytica 1 (50) 1 (50)   
  - P. aeruginosa 1 (50) 1 (50)   
  1. Values are expressed as frequency (percentage) for qualitative variables and as median (interquartile range) for quantitative variables. n: number of patients. p-value: significant value. IL-6 interleukin-6, CLABSI central line-associated bloodstream infection, CAUTI catheter-associated urinary tract infection, VAP ventilator-associated pneumonia
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