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Table 2 Blood parameters and microbiological data

From: The different manifestations of COVID-19 in adults and children: a cohort study in an intensive care unit

 

Total

n = 20

Adults

n = 16

Children

n = 4

p-value

Biomarkers

 Mid-regional pro-adrenomedullin (nmol/L)

0.85 (0.65–1.15)

0.78 (0.64–0.88)

1.72 (1.55–2.77)

0.017

 Procalcitonin (ng/mL)

0.22 (0.12–0.48)

0.19 (0.11–0.37)

5.7 (1.3–7.77)

0.023

 C-reactive protein (mg/L)

181.5 (62.5–237.7)

146.95 (57.58–192.98)

328.2 (252.8–351.15)

0.005

 Troponines (ng/mL)

0.004 (0.002–0.035)

0.003 (0.002–0.014)

0.09 (0.01–2.85)

0.039

 NT-proBNP

2414 (59–4840)

59 (55.5–375)

4057 (2629–18,211)

0.034

Blood samples

 Lymphocytes (/mm3)

1000 (700–1175)

1000 (700–1100)

1100 (475–8175)

0.703

 Prothrombin time (%)

84.5 (65.6–94.8)

88 (83.3–96.8)

56.4 (47.5–63.6)

0.006

 Triglycerides (mg/dL)

391 (180.5–603.5)

413 (255–623)

158 (116–167)

0.015

 D-dimer, at admission (mg/L)

2.45 (1.1–5)

2.45 (0.82–4.46)

3.94 (1.35–7)

0.571

 D-dimer, maximum (mg/L)

6.3 (2.1–8.6)

5.45 (1.89–9.98)

6.75 (5.63–8.33)

0.539

 Ferritin, maximum (ug/L)

910 (359.7–3614.5)

999.5 (311.1–4210.5)

714.8 (567–1369.25)

0.637

 Lactate dehydrogenase, maximum (IU/L)

838 (760–1464)

1053.5 (711–1616)

800 (791–819)

0.576

 IL-6, maximum (pg/mL)

460.5 (52.5–1000)

709.5 (24.7–1000)

141.75 (61.1–804.75)

0.829

Microbiological data

 Healthcare-associated infection, n (%)

8 (40)

8 (50)

0 (0)

0.103

 CLABSI, n (%)

7 (35)

7 (43.8)

  

  - S. epidermidis

5 (71.4)

5 (71.4)

  

  - K. pneumoniae

1 (14.3)

1 (14.3)

  

  - C. albicans

1 (14.3)

1 (14.3)

  

 CAUTI, n (%)

5 (25)

5 (31.3)

  

  - P. aeruginosa

2 (40)

2 (40)

  

  - K. pneumoniae

1 (10)

1 (10)

  

  - E. coli

2 (40)

2 (40)

  

 VAP, n (%)

2 (10)

2 (40)

  

  - R. ornithinolytica

1 (50)

1 (50)

  

  - P. aeruginosa

1 (50)

1 (50)

  
  1. Values are expressed as frequency (percentage) for qualitative variables and as median (interquartile range) for quantitative variables. n: number of patients. p-value: significant value. IL-6 interleukin-6, CLABSI central line-associated bloodstream infection, CAUTI catheter-associated urinary tract infection, VAP ventilator-associated pneumonia