Skip to main content

Table 3 Laboratory data of 286 inpatients at admission and at a secondary time point between 48 and 96 h of admission. Median and interquartile ranges are presented. The P value is calculated between patients who survived and did not survive. aPTT, activated partial thromboplastin time; Alk Phosphatase, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CI, confidence interval; CRP, C-reactive protein; INR, international normalized ratio; LDH, lactate dehydrogenase; PT, prothrombin time

From: Higher comorbidities and early death in hospitalized African-American patients with Covid-19

Laboratory values
(reference range)
Time of determination
(n)
Survivors Non-survivors 95% CI P value
Median (Inter Quartile Range)
Hematologic parameters
Hemoglobin
(12–16 g/dL)
At admission (286) 12.3 (11.0–14.0) 12.7 (11.3–14.3) −0.9 - 0.1 0.13
48–96 h (228) 12.0 (10.15–13.1) 11.7 (10.5–13.3) −0.6 - 0.5 0.83
Leukocyte count
(3.5–10.8 K/μL)
At admission (285) 7.2 (5.4–9.3) 8.6 (6.4–11.3) −2.3 - -0.7 < 0.001
48–96 h (228) 6.5 (5.1–9.4) 10.6 (7.8–14.3) −4.9 - -2.7 < 0.001
Neutrophil Count
(1.7–7 K/μL)
on admission (270) 5.8 (3.8–7.8) 7.3 (4.8–10.0) − 2.3 - -0.8 < 0.001
48–96 h (205) 5.4 (3.4–7.6) 8.9 (6.4–12.5) −4.8, − 2.5 < 0.001
Lymphocyte count
(0.9–2.9 K/μL)
on admission (260) 0.9 (0.7–1.1) 0.8 (0.6–1.1) −5.4e - -5, 0.2 0.04
48–96 h(205) 1.0 (0.8–1.3) 0.8 (0.5–1.2) 0.1–0.3 0.002
Neutrophil Lymphocyte count (NLR) on admission (260) 5.4 (3.7–8.1) 8.3 (5.3–13.7) −3.8 - -1.4 < 0.001
48–96 h (204) 4.7 (3.3–7.0) 10.0 (6.06–19.5) −6.7 - -3.2 < 0.001
Eosinophil count
(0.0–0.8 K/μL)
on admission (255) 0.03 (0.01–0.07) 0.02 (0.01–0.04) 0.002–0.01 < 0.001
48–96 h (203) 0.05 (0.02–0.1) 0.01 (0.01–0.04) 0.01–0.03 < 0.001
Platelet count
(130–400 K/μL)
on admission (283) 204 (158–266) 200 (147–260) −11.0 - 28 0.40
48–96 h (225) 229 (153–338) 194 (150–280) − 5.9 - 53.9 0.11
Blood Chemistry
Sodium
(136–145 mmol/L)
on admission (286) 136 (133–138) 136 (132–141) − 2.0 - 1.0 0.51
48–96 h (237) 138 (136–140) 142 (137–147) − 5.9 - -2.0 < 0.001
Potassium
(3.5–5.1 mmol/L)
on admission (286) 4.2 (3.8–4.8) 4.4 (3.9–5.0) − 0.4 - 4.9e-5 0.04
48–96 h (235) 4.3 (4.0–4.6) 4.4 (3.9–5) − 0.4 - 5.2e-5 0.05
Bicarbonate
(23.0–28.0 mmol/L)
on admission (196) 25 (22–30) 22 (19–26) 1.0–4.9 0.001
48–96 h (143) 24 (21–28) 21 (18–24) 1.6–5.0 <.0.001
Chloride
(98–107 mmol/L)
on admission (285) 100 (94–103) 100 (96–105) − 3.9 - 3.5e-5 0.09
48–96 h (238) 102 (96–106) 107 (101–113) − 8.0 - -3.0 < 0.001
Magnesium
(1.9–2.7 mg/dL)
on admission (159) 2 (1.8–2.2) 2.2 (1.9–2.6) − 0.30 - -2.9e-5 0.014
48–96 h (164) 2.2 (1.8–2.3) 2.4 (2.1–2.7) − 0.4 - -0.2 < 0.001
BUN
(7–25 mg/dL)
on admission (285) 22 (14–38) 33 (19–54) − 14.0 - -5.0 < 0.001
48–96 h (235) 20 (14–40) 38 (23–67) − 22.0 - -10 < 0.001
Serum creatinine
(0.7–1.3 mg/dL)
on admission (286) 1.3 (1.0–2.4) 1.7 (1.2–2.6) − 0.5 - -0.1 0.008
48–96 h (237) 1.2 (0.8–2.3) 1.6 (1.1–3.1) −0.6 - -0.1 0.003
Glucose – random
(70–99 mg/dL)
on admission (286) 128 (104–184) 182 (129–275) − 61.0 - -23.0 < 0.001
48–96 h (240) 103 (84–140) 163 (119–269) − 72.9 - -35.9 < 0.001
AST
(13–39μ/L)
on admission (284) 40 (26–65) 52 (38–83) − 19.0 - -5.0 < 0.001
48–96 h (224) 49 (28–66) 64 (37.7–106.2) − 29.0 - -8.0 < 0.001
ALT
(7–52μ/L)
on admission (284) 24 (16–38) 29 (19–44) − 7.0 - 0.1 0.11
48–96 h (224) 28 (17–52) 34 (22–57) − 10.0 - 2.0 0.22
Alk Phosphatase
(34–104 U/L)
on admission (284) 64 (49–78) 66 (54–96) − 15.0 - -1.0 0.02
48–96 h (223) 59 (46–78) 75 (52–111) − 27.0 - -7.0 < 0.001
Bilirubin
(0.3–1 mg/dL)
on admission (280) 0.5 (0.4–0.8) 0.6 (0.5–0.8) − 0.1 - 5.0e-5 0.28
48–96 h (219) 0.5 (0.4–0.8) 0.7 (0.5–.9) − 0.2 - -5.4e-5 0.002
Total protein
(6–8.3 g/dL)
on admission (282) 7 (6.5–7.3) 6.7 (6.4–7.2) −2.6e-5 - 0.3 0.12
48–96 h (219) 6.2 (5.9–6.6) 6 (5.5–6.7) − 6.0e-5 - 0.4 0.10
Albumin
(3.5–5.7 g/dL)
on admission (283) 3.6 (3.2–4.0) 3.4 (3.1–3.6) 0.1–0.3 < 0.001
48–96 h (223) 3.0 (2.7–3.2) 2.8 (2.5–3.0) 0.1–0.3 < 0.001
LDH
(14–271 U/L)
on admission (201) 379 (280–500) 551 (411–743) 106.0–22,849 < 0.001
48–96 h (82) 406 (278–553) 638 (444.5–867) 106.9–339.0 < 0.001
CRP
(< 10 mg/L)
on admission (201) 117 (63–197) 180 (128–283) −97.0 - -36.9 < 0.001
48–96 h (85) 96 (41–185) 283 (188–338) −200.0 - -88.9 < 0.001
Troponin I
(<=0.15 ng/mL)
on admission (170) 0.03 (0.02–0.12) 0.08 (0.02–0.21) 3.6e-5 - 0.06 0.010
48–96 h (61) 0.11 (0.02–0.26) 0.15 (0.06–0.40) − 0.03 - 0.18 0.30
Ferritin
(14–233 ng/mL)
on admission (190) 654.5 (303–1151) 955 (539.0–2114.6) 118.5–566.5 0.002
48–96 h (95) 768.5 (439–1821) 1614.1 (499.7–2801.5) − 37.3, −  1036.7 0.08
Procalcitonin
(0–0.10 ng/mL)
on admission(172) 0.32 (0.10–0.96) 1.03 (0.36–3.78) 0.19–0.88 < 0.001
48–96 h (69) 0.34 (0.25–2.47) 1.68 (0.41–7.35) 4.75e-5 - 2.77 0.049
D-dimer
< 0.4 mcg/ml
on admission (50) 3.3 (1.3–5.2) 1.5 (0.5–5.2) −1.02 - 2.6 0.39
48–96 h (43) 0.5 (0.5–1.5) 3.0 (1.1–7.5) − 4.5 - -0.2 < 0.001
Coagulation Parameters
aPTT
(25.4–38.6 s)
on admission (126) 29.9 (28.4–32.4) 29.0 (26.9–33.6) −1.9 - 1.5 0.68
48–96 h (44) 30.7 (28.0–36.2) 31.1 (27.9–39.0) − 6.3 - 6.3 0.99
PT
(10.8–13.7 s)
on admission (113) 13.0 (12.2–13.7) 13.5 (12.6–15.4) 5.1–1.3 0.04
48–96 h(43) 13.1 (11.9–15.2) 17.2 (13.3–20.2) 4.94e-5 - 6.7 0.04
INR (1 U) on admission (113) 1.1 (1.0–1.1) 1.1 (1.0–1.3) − 7.12e-6 - 0.10 0.07
48–96 h (41) 1.0 (1.0–1.2) 1.4 (1.1–1.6) 7.49e-6 - 0.50 0.02
\