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Table 4 Frequencies of IFNL3 and IFNL4 haplotypes concerning spontaneous HCV elimination (cases) and persistent HCV infection (controls)

From: Polymorphism rs368234815 of interferon lambda 4 gene and spontaneous clearance of hepatitis C virus in haemodialysis patients: a case-control study

SNPs Haplotype Haplotype Frequencies Case, Control
Frequencies
Chi Square P Value Pcorr
Value
OR (95%CI), P Value OR (95%CI)§, P Value
rs12980275_rs4803217_rs12979860_rs368234815_rs8099917 A_C_C_TT_T 0.562 0.667, 0.485 10.590 0.0011 0.0060 2.294 (1.412–3.727), 0.0007 Reference
G_A_T_∆G_G 0.174 0.102, 0.227 8.543 0.0035 0.0190 0.380 (0.197–0.732), 0.0030 0.326 (0.167–0.638), 0.0008
G_A_T_∆G_T 0.121 0.110, 0.130 0.289 0.5909 1.0000 0.819 (0.411–1.632), 0.5692 0.611 (0.301–1.241), 0.1706
G_C_C_TT_T 0.043 0.037, 0.046 0.164 0.6855 1.0000 0.736 (0.241–2.253), 0.5901 0.543 (0.175–1.685), 0.2847
A_A_T_∆G_T 0.020 0.008, 0.028 1.583 0.2083 0.7840 0.263 (0.030–2.280), 0.1934 0.196 (0.022–1.709), 0.1024
G_A_T_TT_G 0.016 0.015, 0.016 0.013 0.9081 1.0000 0.894 (0.147–5.434), 0.9032 0.652 (0.106–3.997), 0.6415
  1. P-value calculated using the permutation test and a total of 1000 permutations
  2. All other haplotypes pooled together were used as the reference
  3. §The most common haplotype was used as the reference