univariable analysis | multivariable analysis | ||||||
---|---|---|---|---|---|---|---|
Variable | OR | 95% CI | P value | OR | 95% CI | P value | |
Age at study inclusion (per 5-year increment) | 1.36 | 1.17–1.58 | < 0.001 | 1.28 | 1.06 | 1.55 | 0.0089 |
Nadir CD4+ count (per 100-cell/mcL increment) | 0.81 | 0.66–1.01 | 0.06 | 1.16 | 0.88 | 1.53 | 0.286 |
Duration of specialist care (per 10-year increment) | 2.25 | 1.42–3.57 | < 0.001 | 0.73 | 0.22 | 2.48 | 0.617 |
Duration of ART (per 10-year increment) | 2.96 | 1.60–5.49 | < 0.001 | 1.87 | 0.37 | 9.46 | 0.448 |
HIV risk group | |||||||
Heterosexual contact vs. IDU | 0.54 | 0.21–1.38 | 0.362 | 0.63 | 0.18 | 2.19 | 0.668 |
Homosexual contact vs. IDU | 0.33 | 0.14–0.75 | 0.005 | 0.46 | 0.15 | 1.45 | 0.168 |
Other vs. IDU | 2.19 | 0.45–10.5 | 0.071 | 1.33 | 0.23 | 7.51 | 0.384 |
Unknown vs. IDU | 0.56 | 0.18–1.79 | 0.528 | 0.59 | 0.14 | 2.45 | 0.633 |
Viral rebound following complete suppression | 2.45 | 1.30–4.59 | 0.005 | 1.32 | 0.58 | 3.01 | 0.503 |
Previous treatment with AZT | 2.00 | 1.06–3.80 | 0.0336 | 0.67 | 0.25 | 1.77 | 0.422 |
Previous treatment with ‘D’ drugs (ddI, ddC, d4T) | 4.13 | 1.92–8.91 | < 0.001 | 2.11 | 0.69 | 6.42 | 0.188 |