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Table 3 Assessment of Prescription Quality According to Drug

From: Antifungal stewardship in a tertiary care paediatric hospital: the PROAFUNGI study

Drug

Patients, n

Prescriptions Evaluated, n

Non-optimal Prescriptions (n, %)

Cause a

Liposomal amphotericin B

27

105

12 (11%)

- Unnecessary (9)

- Inappropriate (2)

- Inadequate: incorrect dose (5), incorrect duration (7), disagreement with institutional protocol b (5)

Posaconazole

12

32

1 (3%)

- Inadequate, incorrect dose (1)

Anidulafungin

11

29

3 (10%)

- Unnecessary (3)

Fluconazole

11

25

1 (4%)

- Inadequate, incorrect dose (1)

Isavuconazole

2

9

5 (56%)

- Inadequate: disagreement with institutional protocol** (5)

Micafungin

3

7

2 (29%)

- Unnecessary (2)

- Inadequate: disagreement with institutional protocol b (2)

Voriconazole

2

5

0

N/A

Caspofungin

1

4

0

N/A

Itraconazole

2

3

0

N/A

  1. Abbreviations: N/A not applicable
  2. a The same prescription may not be optimal for more than one reason
  3. b Disagreement with institutional protocol, when available