Skip to main content

Table 3 Main interventions and outcomes in patients with diabetes and Middle East Respiratory Syndrome (MERS) compared to patients with no diabetes and MERS

From: Critically ill patients with diabetes and Middle East respiratory syndrome: a multi-center observational study

Variables Diabetes
N = 171
No Diabetes
N = 179
P-value
Interventions
 Non-invasive positive pressure ventilation – no. (%) 64 (37.4) 43 (24.0) 0.007
 Invasive ventilation – no. (%) 153 (89.5) 146 (81.6) 0.04
  Duration, median (Q1, Q3) 9.5 (4.0,17.0) 9.0 (4.0, 16.0) 0.68
 Neuromuscular blockade – no. (%) 55 (32.2) 78 (43.6) 0.03
 High-frequency oscillation ventilation – no. (%) 16 (9.4) 10 (5.6) 0.18
 ECMO – no. (%) 6 (3.5) 16 (8.9) 0.04
 Nitric oxide – no. (%) 28 (16.4) 16 (8.9) 0.04
 Prone positioning – no. (%) 14 (8.2) 19 (10.6) 0.44
  Duration, median (Q1, Q3) 3.0 (2.0,3.0) 3.0 (2.0, 3.0) 0.97
 Any oxygen rescue therapy – no. (%) 73 (42.7) 84 (46.9) 0.43
 Vasopressors – no. (%) 147 (86.0) 129 (72.1) 0.002
  Duration, median (Q1, Q3) 6.5 (4.0,13.0) 6.0 (3.0, 14.0) 0.83
Blood transfusion – no. (%) 59 (34.5) 58 (32.4) 0.68
Antivirals – no. (%)
 Both interferon and ribavirin – no. (%) 70 (40.9) 47 (26.3) 0.02^
 Interferon only – no. (%) 4 (2.3) 5 (2.8)
 Ribavirin only – no. (%) 10 (5.8) 8 (4.5)
 Oseltamivir – no. (%) 89 (52.0) 107 (59.8) 0.15
Corticosteroids – no. (%) 100 (58.5) 75 (41.9) 0.002
Renal replacement therapy – no. (%) 103 (60.2) 71 (39.7) 0.0001
 Duration, median (Q1, Q3) 8.0 (4.0,14.0) 8.0 (3.0, 14.0) 0.92
Intravenous immunoglobins – no. (%) 9 (5.3) 15 (8.4) 0.25
Tracheostomy – no (%) 5 (2.9) 9 (5.0) 0.32
Outcomes
 ICU mortality – no. (%) 133 (77.8) 95 (53.1) < 0.0001
 Hospital mortality – no. (%) 136 (79.5) 102 (57.0) < 0.0001
 90-day mortality – no. (%) 135 (78.9) 98 (54.7) < 0.0001
 28-day mortality – no. (%) 127 (74.3) 90 (50.3) < 0.0001
 14-day mortality – no. (%) 89 (52.0) 76 (42.5) 0.07
 ICU length of stay (days), median (Q1, Q3) 11.0 (6.0,19.0) 8.0 (5.0, 17.0) 0.05
 Hospital length of stay (days), median (Q1, Q3) 18.0 (10.0,33.0) 20.0 (10.0, 37.0) 0.63
  1. ECMO extracorporeal membrane oxygenation, ICU Intensive care unit. The denominator of the percentage is the total number of subjects in the group