Table 3 Subgroup analysis of drug resistance by type of otitis media
From: Bacterial otitis media in sub-Saharan Africa: a systematic review and meta-analysis
Bacterial isolate | Type of otitis media, prevalence % (95% CI) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Patients with CSOM | Patients with OM | Pediatric patients OM | |||||||
Pooled prevalence (%) | No of study | I2 (%) | Pooled prevalence (%) | No of study | I2 (%) | Pooled prevalence (%) | No of study | I2 (%) | |
Ampicillin | 70(54–86) | 8 | 98.56 | 69(48–90) | 7 | 99.09 | 94(91–98) | 2 |  |
Cotrimoxazole | 63(47–80) | 7 | 98.03 | 41(11–72) | 6 | 99.58 | 90(78–100) | 3 |  |
Amoxicillin | – | – | – | 62(37–87) | 5 | 98.78 | 85(81–89) | 2 |  |
Ceftazidime | 52(28–76) | 4 | 97.09 | 7(1–16) | 3 |  | 57(47–66) | 1 |  |
Chloramphenicol | 32(21–48) | 8 | 95.98 | 25(13–38) | 6 | 97.87 | 55(45–64) | 1 |  |
Ciprofloxacin | 19(12–25) | 10 | 94.36 | 16(9–24) | 6 | 94.23 | 34(12–56) | 3 |  |
Gentamycin | 23(15–31) | 11 | 96.54 | 26(13–40) | 6 | 98.25 | 55(34–75) | 4 | 92.92 |
Amoxicillin- Clavulanic acid | 53(32–74) | 7 | 98.76 | 47(8–86) | 4 | 99.48 | 61(13–100) | 4 | 99.59 |
Erythromycin | 41(16–66) | 6 | 98.91 | 38(6–71) | 5 | 99.43 | 81(68–93) | 3 |  |
Cefuroxime | 64(60–69) | 2 |  | 17(14–20) | 2 |  | 60(27–93) | 4 | 98.08 |
Ceftriaxone | 32(18–46) | 8 | 97.73 | 18(10–26) | 5 | 91.71 | 75(58–92) | 4 | 92.19 |
Tetracycline | 37(10–63) | 4 | 98.85 | 20(6–35) | 3 |  | 98(88–100) | 1 |  |