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Table 2 Sensitivities and their 95%CI for all index tests in different subgroups

From: Diagnostic accuracy and utility of three dengue diagnostic tests for the diagnosis of acute dengue infection in Malaysia

Parameter

ViroTrack Dengue Acute NS1

SD Dengue NS1 Ag ELISA

SD Bioline DD NS1 only

SD Bioline DD IgM only

SD Bioline DD IgG only

SD Bioline DD NS1 or IgM

SD Bioline DD NS1 or IgM or IgG

By Serotype

 DENV-1

20/31

20/31

14/31

7/31

3/31

19/31

20/31

64.5 (45.4–80.8)

64.5 (45.4–80.8)

54.8 (36.0–72.7)

22.6 (9.6–41.1)

9.7 (2.0–25.8)

61.3 (42.2–78.2)

64.5 (45.4–80.8)

 DENV-2

23/29

23/29

24/29

3/29

3/29

25/29

27/29

79.3 (60.3–92.0)

79.3 (60.3–92.0)

82.8 (64.2–94.2)

10.3 (2.2–27.4)

10.3 (2.2–27.4)

86.2 (68.3–96.1)

93.1 (77.2–99.2)

 DENV-3

29/30

28/30

28/30

5/30

3/30

29/30

29/30

96.7 (82.8–99.9)

93.3 (77.9–99.2)

93.3 (77.9–99.2)

16.7 (5.6–34.7)

10.0 (2.1–26.5)

96.7 (82.8–99.9)

96.7 (82.8–99.9)

 DENV-4

0/1

0/1

0/1

0/1

0/1

0/1

0/1

0 (0–97.5)

0 (0–97.5)

0 (0–97.5)

0 (0–97.5)

0 (0–97.5)

0 (0–97.5)

0 (0–97.5)

By day of illness

 First 5 days

102/157

109/160

93/160

51/160

33/160

117/160

128/160

65.0 (57.0–72.4)

68.1 (60.3–75.3)

58.1 (50.1–65.9)

31.9 (24.7–39.7)

20.6 (14.6–27.7)

73.1 (65.6–79.8)

80.0 (73.0–85.9)

 > = 6 days

37/66

42/67

26/67

52/67

30/67

55/67

59/67

56.1 (43.3–68.3)

62.7 (50.0–74.2)

38.8 (27.1–51.5)

77.6 (65.8–86.9)

44.8 (32.6–57.4)

82.1 (70.8–90.4)

88.1 (77.8–94.7)

By dengue infection status

 Primary

99/134

104/137

88/137

61/137

7/137

113/137

113/137

73.9 (65.6–81.1)

75.9 (67.9–82.8)

64.2 (55.6–72.2)

44.5 (36.0–53.3)

5.1 (2.1–10.2)

82.5 (75.1–88.4)

82.5 (75.1–88.4)

 Secondary

40/89

47/90

31/90

42/90

56/90

59/90

74/90

44.9 (34.4–55.9)

52.2 (41.4–62.9)

34.4 (24.7–45.2)

46.7 (36.1–57.5)

62.2 (51.4–72.2)

65.6 (54.8–75.3)

82.2 (72.7–89.5)

  1. The italic numbers shown before the sensitivity estimates are true positives over all disease-positives for the respective assay