Table 1 Diagnostic accuracy estimates and their 95%CI for all index tests

Sensitivity^a, % (95%CI)

139/223

151/227

119/227

103/227

63/227

172/227

187/227

62.3%

66.5%

52.4%

45.4%

27.8%

75.8%

82.4%

(55.6–68.7)

(60.0–72.6)

(45.7–59.1)

(38.8–52.1)

(22.0–34.1)

(69.7–81.2)

(76.8–87.1)

Specificity^a, % (95%CI)

249/262

250/262

256/262

258/262

233/262

253/262

229/262

95.0%

95.4%

97.7%

98.5%

88.9%

96.6%

87.4%

(91.7–97.3)

(92.1–97.6)

(95.1–99.2)

(96.1–99.6)

(84.5–92.5)

(93.6–98.4)

(82.8–91.2)

PPV^a, % (95%CI)

139/152

151/163

119/125

103/107

63/92

172/181

187/220

91.4%

92.6%

95.2%

96.3%

68.5%

95.0%

85.0%

(85.8–95.4)

(87.5–96.1)

(89.8–98.2)

(90.7–99.0)

(58.0–77.8)

(90.8–97.7)

(79.6–89.4)

NPV^a, % (95%CI)

249/333

250/326

256/364

258/382

233/397

253/308

229/269

74.8%

76.7%

70.3%

67.5%

58.7%

82.1%

85.1%

(69.8–79.4)

(71.7–81.2)

(65.3–75.0)

(62.6–72.2)

(53.7–63.6)

(77.4–86.3)

(80.3–89.2)

LR +

(95%CI)

12.6

14.5

22.9

29.7

2.5

22.1

6.5

(7.32–21.5)

(8.29–25.4)

(10.3–51.0)

(11.1–79.4)

(1.7–3.8)

(11.6–42.1)

(4.7–9.1)

LR -

(95%CI)

0.40

0.35

0.49

0.56

0.81

0.25

0.20

(0.33–0.47)

(0.29–0.42)

(0.42–0.56)

(0.49–0.63)

(0.74–0.89)

(0.20–0.32)

(0.15–0.27)

AUC

(95%CI)

0.79

0.81

0.75

0.72

0.58

0.86

0.85

(0.75–0.82)

(0.78–0.84)

(0.72–0.78)

(0.69–0.75)

(0.55–0.62)

(0.83–0.89)

(0.82–0.88)

DOR

(95%CI)

31.7

41.4

47 .0

53.6

3.1

87.9

32.4

(17.2–58.5)

(22.0–77.9)

(20.5–108.0)

(20.0–143.0)

(1.9–5.0)

(42.8–180.0)

(19.7–53.4)