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Table 1 Diagnostic accuracy estimates and their 95%CI for all index tests

From: Diagnostic accuracy and utility of three dengue diagnostic tests for the diagnosis of acute dengue infection in Malaysia

ParameterViroTrack Dengue Acute NS1SD Dengue NS1 Ag ELISASD Bioline DD NS1 onlySD Bioline DD IgM onlySD Bioline DD IgG onlySD Bioline DD NS1 or IgMSD Bioline DD NS1 or IgM or IgG
Sensitivitya, % (95%CI)139/223151/227119/227103/22763/227172/227187/227
62.3%66.5%52.4%45.4%27.8%75.8%82.4%
(55.6–68.7)(60.0–72.6)(45.7–59.1)(38.8–52.1)(22.0–34.1)(69.7–81.2)(76.8–87.1)
Specificitya, % (95%CI)249/262250/262256/262258/262233/262253/262229/262
95.0%95.4%97.7%98.5%88.9%96.6%87.4%
(91.7–97.3)(92.1–97.6)(95.1–99.2)(96.1–99.6)(84.5–92.5)(93.6–98.4)(82.8–91.2)
PPVa, % (95%CI)139/152151/163119/125103/10763/92172/181187/220
91.4%92.6%95.2%96.3%68.5%95.0%85.0%
(85.8–95.4)(87.5–96.1)(89.8–98.2)(90.7–99.0)(58.0–77.8)(90.8–97.7)(79.6–89.4)
NPVa, % (95%CI)249/333250/326256/364258/382233/397253/308229/269
74.8%76.7%70.3%67.5%58.7%82.1%85.1%
(69.8–79.4)(71.7–81.2)(65.3–75.0)(62.6–72.2)(53.7–63.6)(77.4–86.3)(80.3–89.2)
LR +
(95%CI)
12.614.522.929.72.522.16.5
(7.32–21.5)(8.29–25.4)(10.3–51.0)(11.1–79.4)(1.7–3.8)(11.6–42.1)(4.7–9.1)
LR -
(95%CI)
0.400.350.490.560.810.250.20
(0.33–0.47)(0.29–0.42)(0.42–0.56)(0.49–0.63)(0.74–0.89)(0.20–0.32)(0.15–0.27)
AUC
(95%CI)
0.790.810.750.720.580.860.85
(0.75–0.82)(0.78–0.84)(0.72–0.78)(0.69–0.75)(0.55–0.62)(0.83–0.89)(0.82–0.88)
DOR
(95%CI)
31.741.447 .053.63.187.932.4
(17.2–58.5)(22.0–77.9)(20.5–108.0)(20.0–143.0)(1.9–5.0)(42.8–180.0)(19.7–53.4)
  1. aThe italic numbers shown before the parameter estimates are number of correct tests over number of all tests for each corresponding parameter