MSSA IE N = 378 | MRSA IE N = 59 | p* | |
---|---|---|---|
Findings < 1 week before hospitalization, n (%) | 212/355 (59.7) | 22/52 (42.3) | 0.051 |
Clinical n (%) | |||
- Fever | 365(96.6) | 55(93.2) | 0.251 |
- Dyspnea | 174(46) | 31(52.5) | 0.361 |
- Constitutional syndrome | 81(21.4) | 11(18.6) | 0.689 |
- Murmur | 199(52.6) | 30(50.8) | 0.822 |
- Hepatomegaly | 66(17.4) | 8(13.6) | 0.420 |
- Splenomegaly | 48(12.7) | 9(15.3) | 0.615 |
- CNS | 156(41.3) | 18(30.5) | 0.116 |
Encephalopathy | 76 (20.1) | 9 (15.3) | 0.4 |
Meningitis | 20 (5.3) | 1 (1.69) | 0.3 |
Abscess | 6 (1.6) | 0 | 1 |
Embolic non-hemorrhagic stroke | 62 (16.4) | 7 (11.9) | 0.43 |
Embolic hemorrhagic stroke | 11 (2.9) | 2 (3.39) | 0.68 |
Hemorrhagic stroke with no previous Embolism | 22 (5.8) | 2 (3.39) | 0.75 |
- Renal embolism | 6(1.6) | 0 | 1 |
- Spleen embolism | 22(5.8) | 5(8.5) | 0.387 |
- Large vessel embolism | 30(7.9) | 5(8.5) | 0.799 |
- Pulmonary embolism | 27(7.1) | 8(13.6) | 0.119 |
- Roth’s spots | 13 (3.4) | 0 | 0.228 |
- Conjunctival hemorrhage | 15(3.9) | 0 | 0.230 |
- Endophthalmitis | 0 | 1 (1.7) | 0.127 |
- Cutaneous manifestation | 108 (28.6) | 11 (18.6) | 0.093 |
- Petechiae | 80 (21.2) | 7 (11.9) | 0.115 |
- Janeway lesions | 53(14) | 3(5.1) | 0.054 |
- Osler’s nodes | 61(16.1) | 4(6.8) | 0.057 |
- Splinter hemorrhage | 43(11.4) | 5(8.5) | 0.496 |
- Duke vascular or embolic phenomena | 120(31.7) | 12(20.4) | 0.072 |
- Duke immunological phenomena | 29 (7.7) | 1 (1.7) | 0.099 |
- Osteoarticular involvement | 52(13.8) | 8(13.6) | 0.98 |
- Acute kidney failure during hospitalization | 159(42) | 22(37.3) | 0.469 |
- Heart failure | 171 (45.2) | 25(42.4) | 0.643 |
Grade III-IV | 90 (23.8) | 18 (30.5) | 0.3 |
- Severe sepsis/Septic shock | 97(25.7) | 14(23.7) | 0.751 |
- Acute pulmonary edema | 93(24.6) | 17(28.8) | 0.446 |
Echocardiographic findings, n (%) ** | |||
- Diagnostic data | 336 (88.9) | 49(83.1) | 0.34 |
- Vegetation | 249(65.9) | 43 (72.9) | 0.615 |
- Perivalvular lesion | 107(28.3) | 9(15.3) | 0.043 |
- Pseudoaneurysm | 14(3.7) | 1(1.7) | 0.7 |
- Fistula in valvular system | 8(2.1) | 2(3.4) | 0.63 |
- Valvular system rupture or perforation | 63(16.7) | 6(10.2) | 0.226 |
- Prosthesis dehiscence or dysfunction | 23(6.1) | 5(8.5) | 0.39 |
- Pericardial effusion | 14(3.7) | 2(4.4) | 1 |
IE classification, n(%) | |||
Possible | 25 (6.6) | 7(11.9) | |
Definite | 352(93.1) | 52(88.1) | 0.18 |