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Table 1 Main characteristics of premature neonates colonized or infected with Klebsiella pneumoniae during the outbreak in 2017

From: Successful control of an extended-spectrum beta-lactamase-producing Klebsiella pneumoniae ST307 outbreak in a neonatal intensive care unit

CaseSexInterval*Gestational age, (week + day)Birth weight, (g)Major invasive procedureType of infectionPositive culture specimens (date)Exposure to RN 33d (date)Empirical antibiotic regimenOutcome (cause of death)
1bM5.424 + 0640CVC, MVCLABSIB (8/15)NOVA, TZP, MERCured
2F39.431 + 51505CVC, MVCLABSIU (9/1), B (9/8)NOVA, MER, CCDeath (sepsis)
3cM48.424 + 0640CVC, MV, Explorative laparotomyCLABSIB (9/27)NOVA, TZP, MERDeath (sepsis)
4M5.029 + 51150CVC, MV, Explorative laparotomyColonizedS (11/1)Yes (11/17–12/18)VA, TZP, MERCured
5F13.526 + 61042CVCNEC, BSIB (12/6)Yes (12/21)VA, TZP, MERCured
6F41.426 + 1790CVC, MV, PDA ligationCLABSIB (12/10)NOVA, TZP, MERCured
7F21.927 + 21215CVCCLABSIB (12/29)NOVA, TZP, MERDeath (sepsis)
  1. a Interval from birth till when detected positive for ESBL-KPN
  2. b Index case
  3. c Cases 1 and 3 are of the same neonate
  4. d RN (registered nurse) 33 was positive in the rectal swab culture
  5. CVC central venous catheter, MV mechanical ventilation, PDA patent ductus arteriosus, CLABSI central line-associated bloodstream infection, NEC necrotizing enterocolitis, B blood, U urine, S sputum, VA vancomycin, TZP piperacillin/tazobactam, MER meropenem, CC clindamycin