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Table 1 Characteristics of MDR-TB patients in HCMC from 2011 to 2015

From: Risk factors for poor treatment outcomes of 2266 multidrug-resistant tuberculosis cases in Ho Chi Minh City: a retrospective study

Characteristicn (%)
Total2266
Age at diagnosis (years, median (IQR))43 (33–53)
 > 60 years old197 (8.7%)
 18–60 years old2037 (89.9%)
 < 18 years old32 (1.4%)
Male1715 (75.7%)
Site of disease
 Pulmonary2237 (98.7%)
 Multi-organ a37 (1.7%)
 Extra pulmonary66 (3%)
  Lymphadenitis22
  Meningitis21
  Pleuritis8
  Bone and vertebral4
  Soft tissue1
  Gastro-intestinal1
Registration group
 New128 (5.6%)
 Relapse678 (29.9%)
 Failure of regimen 1512 (22.6%)
 Failure of regiment 2852 (37.6%)
 Treatment after lost to follow-up47 (2.1%)
 Transfer1 (0%)
 Other46 (2%)
 Not recorded2 (0.1%)
Regimen of previous treatment
 I913 (40.3%)
 II1012 (44.6%)
 III2 (0.1%)
 IV54 (2.4%)
 No history of previous treatment128 (5.6%)
 Unclear history157 (7%)
BMI at diagnosis (kg/m2)n = 1815
 Median (IQR)17.86 (15.76–19.96)
 Overweight (BMI ≥ 25)46 (2.5%)
 Normal BMI (BMI: 18.5- < 25)721 (39.7%)
 Mild underweight (BMI: 17- < 18.5)343 (18.9%)
 Moderate underweight (BMI: 16- < 17)250 (13.8%)
 Severe underweight (BMI < 16)456 (25.1%)
HIV positive204/2136 tested for HIV (9.6%)
Diabetes359/1189 (30.2%)
 Unknown history of diabetes1077 (47.5%)
Initial Diagnosis Method
 DST274 (12.1%)
 Xpert1276 (56.3%)
 Hain705 (31.1%)
 DST of last treatment episode7 (0.3%)
 Missing data4 (0.2%)
AFB smear at baseline
 Positive1748 (77.1%)
   < 1+158 (9%)
  1+895 (51.1%)
  2+357 (20.5%)
  3+275 (15.7%)
  Unknown grade63 (3.7%)
 Negative475 (21%)
 Not recorded43 (1.9%)
Culture at diagnosis
 Positive1371 (60.5%)
 Negative178 (7.8%)
 Non-Tuberculosis Mycobacterium (but Xpert positive)b4 (0.2%)
 Contaminated19 (0.8%)
 Not recorded694 (30.6%)
  1. a involved both pulmonary and extra pulmonary TB
  2. b All four cases of culture positive for Non-Tuberculosis Mycobacterium also had GeneXpert detected Mycobacterium tuberculosis