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Table 2 Characteristics of the infection disease at baseline. Comparison between the two infected groups

From: Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function

 

TOTAL

VIG

BIG

p-valueb

CG

N = 63

N = 38

N = 25

 

N = 36

Time from transplant in days, median (IQR)

303 (213–560)

366 (250–615)

255 (198–460)

0.27

204 (190–232)

Hospitalization, n (%)

29 (46)

13 (34)

16 (64)

0.04

3 (8)

Time of hospital stay in days, n (%)

14 (8–22)

11 (7–15)

16 (12–23)

0.11

25 (16–26)

Symptoms

41 (73)

23 (70)

18 (78)

0.69

2 (6)

 Temperature, °C, (median, IQR)

36.8 (36.4–37.0)

37.0 (36.6–37.0)

36.7 (36.4–36.8)

0.28

36.7 (36.5–36.9)

 Desaturation < 95% AA (n, %)

11 (25)

3 (13)

8 (40)

0.08

0 (0)

 Dyspnea (n, %)

21 (43)

9 (33)

12 (55)

0.23

1 (3)

 Cough (n, %)

28 (54)

16 (52)

12 (57)

0.91

1 (3)

 Sputum (n, %)

23 (43)

10 (32)

13 (59)

0.10

0 (0)

 Coryza (n, %)

12 (23)

7 (21)

5 (25)

0.75

1 (3)

 Auscultator abnormality (n, %)

14 (28)

8 (27)

6 (30)

1.00

0 (0)

Biology

 Leucocytes, G/L (median, IQR)

8190 (5180–1044)

8100 (5950–11,070)

8205 (4695–16,450)

0.49

8280 (6215–9910)

 Hemoglobin, g/dL (median, IQR)

11.6 (10.7–12.3)

11.5 (10.7–12.3)

11.6 (10.1–12.4)

0.97

11.4 (10.4–12.3)

 Platelets, 103 G/L (median, IQR)

250 (216–303)

248 (216–321)

270 (218–302)

0.69

261 (202–329)

 C-Reactive Protein, mg/L (median, IQR)

6.5 (5.0–34.8)

5.5 (5.0–26.3)

8.5 (5.0–55.5)

0.51

5.0 (5.0–9.0)

 Creatininemia, μmol/L (median, IQR)

111 (85–139)

114 (85–143)

105 (86–126)

0.18

89 (76–105)

 GFR, ml/min/1.73 (median, IQR)

55 (44–78)

56 (41–78)

52 (47–74)

0.93

72 (57–81)

 Tacrolimus level, UI/L (median, IQR)

8.8 (7.3–10.8)

8.6 (7.1–10.5)

9.4 (8.0–10.9)

0.91

9.2 (7.7–10.2)

New infiltrate in thoracic TDM (n, %)

7 (11)

3 (9)

4 (20)

0.37

3 (10)

Delta FEV-1 at inclusiona, ml (median, IQR)

−45 (− 188–68)

−50 (−170–60)

−260 (−410–0)

0.05

0 (−95–74)

Antiviral therapy (n, %)

21 (33)

14 (37)

7 (28)

0.65

0 (0)

Antibiotic therapy (n, %)

28 (44)

3 (8)

25 (100)

< 0.01

0 (0)

  1. Abbreviations: BIG bacterial infections group; CG control group; GFR Glomerular filtration rate; TDM tomodensitometry; FEV-1 forced expiratory volume in 1 s; VIG viral infections group
  2. a Inclusion FEV-1 - last FEV-1
  3. b Comparison between the two infected groups, viral and bacterial infections
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BMC Infectious Diseases

ISSN: 1471-2334

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