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Table 5 Head-to-head comparison of different TB diagnostic tests, including Xpert Ultra and the MPT64 test among TB cases1

From: Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting

 All TB cases
n = 31
 MPT64 test performedMicroscopy performed1-step PCR performedNested-PCR performedCulture performed
 n = 31n = 27n = 18n = 11n = 26
 MPT64 test +MPT64 test -Micro-scopy +Micro-scopy -1-step PCR+1-step PCR-Nested-PCR+Nested-PCR-Culture +Culture -
 n = 10n = 21n = 6n = 21n = 6n = 12n = 7n = 4n = 16n = 10
Microscopy +24        
Microscopy -417        
1-step PCR +4242      
1-step PCR -21029      
Nested-PCR +521310    
Nested-PCR -040401    
Culture +3134125722  
Culture -37271502  
Xpert Ultra +2222301140
Xpert Ultra -0303010112
  1. Abbreviations: TB, tuberculosis; PCR, polymerase chain reaction
  2. 1TB cases include both microbiologically confirmed TB cases (n = 26) and clinically diagnosed TB cases (n = 5)