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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains

Fig. 2

Pseudovirus-based phenotypic resistance assay for AZT, TDF, and 3TC. Black columns and white columns represent the K65R/S68G double mutation and K65R mutation pseudoviruses with mutant pol gene sequences obtained from patients, respectively. FC, fold change in IC50 compared with the wild-type pseudoviruses; AZT, zidovudine; TDF, tenofovir; 3TC, lamivudine. Data were averaged from at least three independent experiments

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