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Table 2 Lists and characteristics of included studies

From: Prevalence of Vancomycin resistant enterococci (VRE) in Ethiopia: a systematic review and meta-analysis

Author, publication year

Study period

Study area/ region

Study design

Study subjects

Sample size

Prevalence of enterococci, N (%)

Type of specimen

AST method

Prevalence of VRE, N (%)

Types of isolates (species)

Publication history

Abamecha, 2015 [48]

January to July 2013

Jima University Specialized Hospital, Oromia

CS

Hospitalized patients

150

114 (76.00)

Stool, rectal swabs

Disc diffusion, MIC for VRE

2 (1.8)

E.faecium, E.faecalis, E.gallinarum, E.casseliflavus, E.durans

Published

Abebe, 2014 [37]

July to September 2013

University of Gondar Teaching Hospital, Amhara

CS

HIV positive and HIV negative clients

226

201 (88.94)

Stool

Disc diffusion

11 (5.5)

Not identified to species level

Published

Agegne, 2018 [36]

February to May 2017

West Amhara Hospitals, Amhara

CS

HIV patients on ART

349

220 (63.04)

Stool

Disc diffusion

17 (7.7)

Not identified to species level

Published

Ali, 2018 [35]

February to May, 2017

Dessie Referral Hospital, Amhara

CS

HIV positive and HIV negative clients

300

112 (37.33)

Stool

Disc diffusion

7 (6.3)

Not identified to species level

Published

Ayelign, 2018 [33]

February to June 2015

University of Gondar Hospital, Amhara

CS

Pediatric patients

310

3 (0.97)

Urine

Disc diffusion

1 (33.3)

Not identified to species level

Published

Birri, 2013 [23]

Not reported

Dilla town, SNNPR

CS

Healthy infants aged 3 to 26 weeks

28

53 (189.29)a

Stool

Dilution/MIC

1 (1.9)

E.faecium, E.faecalis, E.avium, E.canintestini, E.maldoratus, E.raffinosus, E.gallinarum

Published

Eshetu, 2017 [44]

April to September 2016

Tikur Anbessa Specialized Hospital, Addis Ababa

CS

Blood stream infection suspects

422

5 (1.18)

Blood

Disc diffusion

3 (60.0)

Not identified to species level

Unpublished

Fentie, 2018 [32]

February to April 2017

University of Gondar teaching Hospital, Amhara

CS

Cancer patients

216

2 (0.93)

Blood, urine, wound swab, ear discharge

Disc diffusion

1 (50.0)

Not identified to species level

Published

Ferede, 2018 [41]

April to May 2016

Black Lion/Tikur Anbesa Specialized

Hospital, Addis Ababa

CS

Patients suspected for UTI, wound infection, septicemia, endocarditis, meningitis

422

15 (3.55)

Blood, urine, body fluid, CSF, Pus

Disc diffusion

1 (6.7)

Not identified to species level

Published

Gebrish, 2019 [47]

February to March 2016

Jimma University Specialized Hospital, Oromia

CS

Hospitalized pediatric patients

52

12 (23.08)

Stool, rectal swabs

Disc diffusion

1 (8.3)

E.faecalis, E.faecalis, E.gallinarum

Published

Jemal, 2017 [34]

July to December 2016

Felege Hiwot Referral Hospital, Amhara

CS

HIV patients on ART

384

4 (1.04)

Blood

Disc diffusion

0.5b (10.0)

Not identified to species level

Unpublished

Lega, 2015 [42]

April to July 2015

Yekatit 12 Hospital Medical

College, Addis Ababa

CS

Diabetic patients

246

2 (0.81)

Urine

Disc diffusion

1 (50.0)

Not identified to species level

Unpublished

Mitiku, 2018 [40]

September 2017 to June 2018

Tikur Anbesa Specialized Hospital, Addis Ababa

CS

Under 5 children with febrile illness

340

11 (3.24)

Blood

Disc diffusion

0.5b (4.2)

Not identified to species level

Unpublished

Mohammed, 2017 [31]

March to May, 2014

University of Gondar Referral

Hospital, Amhara

CS

Patients with wound infections

137

2 (1.46)

Wound swab

Disc diffusion

1 (50.0)

Not identified to species level

Published

Molalign, 2016 [39]

September 2015 to May 2016

Arsho Advanced Medical laboratory, Addis Ababa

CS

UTI patients

712

15 (2.11)

Urine

Dilution/MIC

7 (46.7)

E.faecalis,

E.gallinarum

Unpublished

Sorsa, 2019 [46]

April 2016 to May 2017

Asella teaching and referral hospital, Oromia

CS

Neonates with sepsis

303

6 (1.98)

Blood

Disc diffusion

1 (16.7)

Not identified to species level

Published

Teklehaymanot, 2016

July to September 2015

Tikur Anbessa Specialized Hospital, Addis Ababa

CS

Patients suspected for body fluid pathogens

384

2 (0.52)

CSF, ascites, pleural fluid, synovial fluid

Disc diffusion

0.5 b (16.7)

Not identified to species level

Unpublished

Toru, 2018 [45]

April to September 2016

Jimma University Specialized

Hospital, Oromia

CS

Pediatric patients (<  15 years)

403

22 (5.46)

Urine, blood,

swabs, closed abscess, body fluids, CSF

Disc diffusion

5 (22.7)

Not identified to species level

Published

Woldemariam, 2019 [38]

April to July 2015

St. Paul Specialized Hospital Millennium Medical College, Addis Ababa

CS

Adult diabetic patients

248

6 (2.42)

Urine

Disc diffusion

1 (16.7)

Not identified to species level

Published

Yilema, 2017 [30]

February to May 2014

University of Gondar Teaching Hospital, Amhara

CS

Patients requiring culture and AST

385

24 (6.23)

Urine, blood, wound swabs,

ear discharge, ascites, abscess

Disc diffusion

10 (41.7)

Not identified to species level

Published

  1. AST Antimicrobial Susceptibility testing, ART Antiretroviral Therapy, CS Cross-sectional, CSF Cerebrospinal Fluid, VRE Vancomycin resistant enterococci, MIC Minimum Inhibitory Concentration, SNNPR Southern Nations, Nationalities and Peoples Region
  2. a: multiple enterococcal species were isolated from a single infant; b: 0.5 was added as a continuity correction to include the study in the analysis