TY - JOUR AU - Sun, Zesong AU - Ouyang, Jinming AU - Zhao, Bin AU - An, Minghui AU - Wang, Lin AU - Ding, Haibo AU - Han, Xiaoxu PY - 2020 DA - 2020/02/26 TI - Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China JO - BMC Infectious Diseases SP - 178 VL - 20 IS - 1 AB - The impacts of genetic polymorphisms on drug resistance mutations (DRMs) among various HIV-1 subtypes have long been debated. In this study, we aimed to analyze the natural polymorphisms and acquired DRM profile in HIV-1 CRF01_AE-infected patients in a large first-line antiretroviral therapy (ART) cohort in northeastern China. SN - 1471-2334 UR - https://doi.org/10.1186/s12879-020-4808-3 DO - 10.1186/s12879-020-4808-3 ID - Sun2020 ER -