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Table 4 Laboratory findings of patients with monomicrobial necrotizing fasciitis by gram-negative pathogen and gram-positive pathogen

From: Predictors for gram-negative monomicrobial necrotizing fasciitis in southern Taiwan

VariableGram-negative pathogen (n = 55)Gram-positive pathogen (n = 45)P-value
Total WBCa count
 Leukocytosis ( 12,000/uL)28 (50.9)31 (68.9)0.069
 Leukopenia ( 4000/uL)4 (7.3)2 (4.4)0.554
 Leukocytosis or Leukopenia32 (58.2)33 (73.3)0.114
Differential count
 Band forms > 3%29 (52.7)14 (31.1)0.030*
 Neutrophilia (>  7500/uL)38 (69.1)35 (77.8)0.330
 Lymphocytopenia (<  1000/uL)34 (61.8)23 (51.1)0.282
Hemoglobin (<  10 g/dL)9 (16.4)4 (8.9)0.269
Thrombocytopenia (<  15 × 104/uL)29 (52.7)18 (40.0)0.205
Hypoalbuminemia (<  2.5 g/dL)7 (12.7)1 (2.2)0.054
Hyperlactatemia (> 20 mg/dL)35 (63.6)7 (15.6)< 0.001*
C-reactive protein (<  150 mg/L)40 (72.7)17 (37.8)< 0.001*
Creatinine (μmol/L)180.4 ± 137.2134.5 ± 109.70.072
D-dimer (mg/L)4.3 ± 6.92.6 ± 5.80.222
Fibrinogen (mg/dL)316.5 ± 145.8517.4 ± 164.5< 0.001*
Glucose (mmol/L)9.7 ± 6.410.3 ± 5.20.647
Sodium (mmol/L)135.5 ± 3.5135.0 ± 3.50.544
LRINECb score618 (32.7)28 (62.2)0.003*
PTc (seconds)13.4 ± 4.911.0 ± 2.00.003*
Total bilirubin (mg/dL)1.9 ± 1.91.7 ± 3.90.718
  1. Data was presented as mean (standard deviation) or frequency (%)
  2. Abbreviations: aWBC White blood cell, bLRINEC Laboratory risk indicator for necrotizing fasciitis, cPT Prothrombin time
  3. *: p-value < 0.05