Table 4 Laboratory findings of patients with monomicrobial necrotizing fasciitis by gram-negative pathogen and gram-positive pathogen

 Leukocytosis (≧ 12,000/uL)

28 (50.9)

31 (68.9)

0.069

 Leukopenia (≦ 4000/uL)

4 (7.3)

2 (4.4)

0.554

 Leukocytosis or Leukopenia

32 (58.2)

33 (73.3)

0.114

 Band forms > 3%

29 (52.7)

14 (31.1)

0.030*

 Neutrophilia (>  7500/uL)

38 (69.1)

35 (77.8)

0.330

 Lymphocytopenia (<  1000/uL)

34 (61.8)

23 (51.1)

0.282

Hemoglobin (<  10 g/dL)

9 (16.4)

4 (8.9)

0.269

Thrombocytopenia (<  15 × 10⁴/uL)

29 (52.7)

18 (40.0)

0.205

Hypoalbuminemia (<  2.5 g/dL)

7 (12.7)

1 (2.2)

0.054

Hyperlactatemia (> 20 mg/dL)

35 (63.6)

7 (15.6)

< 0.001*

C-reactive protein (<  150 mg/L)

40 (72.7)

17 (37.8)

< 0.001*

Creatinine (μmol/L)

180.4 ± 137.2

134.5 ± 109.7

0.072

D-dimer (mg/L)

4.3 ± 6.9

2.6 ± 5.8

0.222

Fibrinogen (mg/dL)

316.5 ± 145.8

517.4 ± 164.5

< 0.001*

Glucose (mmol/L)

9.7 ± 6.4

10.3 ± 5.2

0.647

Sodium (mmol/L)

135.5 ± 3.5

135.0 ± 3.5

0.544

LRINEC^b score≧6

18 (32.7)

28 (62.2)

0.003*

PT^c (seconds)

13.4 ± 4.9

11.0 ± 2.0

0.003*

Total bilirubin (mg/dL)

1.9 ± 1.9

1.7 ± 3.9

0.718