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Table 2 Prevalence, clinical setting, infection site of Healthcare-Associated Infections and Antimicrobial Use by year of survey

From: A 2-year point-prevalence surveillance of healthcare-associated infections and antimicrobial use in Ferrara University Hospital, Italy

 

2016

2018

Total

Total No. of Patients, n (%)

530 (48.1)

572 (51.9)

1102 (100.0)

HAI Prevalence (at least one), n (%)

52 (9.8)

63 (11.0)

115 (10.4)

Antimicrobials use prevalence (at least one), n (%)

239 (45.0)

248 (42.8)

487 (44.2)

HAI by clinical setting, n (%)*

52

63

115

Surgery

9 (17.3)

6 (9.5)

15 (13.0)

Medicine

27 (51.9)

40 (63.5)

67 (58.3)

Geriatrics

0 (0.0)

1 (1.6)

1 (0.9)

Intensive Care

7 (13.5)

7 (11.1)

14 (12.2)

Gynaecology/Obstetrics

0 (0.0)

3 (4.8)

3 (2.6)

Paediatrics/Neonatology

1 (1.9)

2 (3.2)

3 (2.6)

Rehabilitation

8 (1.5)

4 (6.3)

12 (10.4)

Post-acute care

0 (0.0)

0 (0.0)

0 (0.0)

Total No. of HAI

63

74

137

HAI by infection site, n (%)

 Pneumonia

17 (27.0)

24 (32.4)

41 (29.9)

 Bloodstream Infections

10 (15.9)

16 (21.6)

26 (19.0)

 Urinary Tract Infections‡

16 (25.4)

5 (6.8)

21 (15.4)

 Gastro-intestinal system infections

6 (9.5)

8 (10.8)

14 (10.2)

 Surgical site infections

4 (6.3)

7 (9.5)

11 (8.0)

 Clinical sepsis

4 (6.3)

4 (5.4)

8 (5.8)

 Infections of ear, nose, throat, larynx and mouth

1 (1.6)

5 (6.8)

6 (4.4)

 Cellulitis, wound, deep soft tissue not involving bone, not related to surgery

0 (0.0)

4 (5.4)

4 (2.9)

 Lower respiratory tract infections

2 (3.2)

1 (1.4)

3 (2.2)

 Others

3 (4.8)

0 (0.0)

3 (2.2)

Total No. of antimicrobials

348

345

693

ATC Antimicrobial classes, n(%)

 J01CR Combinations of penicillins, incl. Beta-lactamase inhibitors

95 (27.3)

82 (23.8)

177 (25.6)

 J01DD Third-generation cephalosporins

72 (20.7)

78 (22.6)

150 (21.6)

 J01MA Fluorochinolones

28 (8.0)

24 (7.0)

52 (7.5)

 J01FA Macrolides

13 (3.7)

20 (5.8)

33 (4.7)

 J02 AC Triazole derivatives

15 (4.3)

17 (4.9)

32 (4.6)

 J01DH Carbapenems

16 (4.6)

15 (4.3)

31 (4.5)

 J01XD Imidazole derivatives

17 (4.9)

14 (4.1)

31 (4.5)

 J01XX08 Linezolid

13 (3.7)

16 (4.6)

29 (4.1)

 J01XA Glycopeptide antibacterials

12 (3.4)

15 (4.3)

27 (3.8)

 J01DB First-generation cephalosporins

11 (3.2)

14 (4.1)

25 (3.6)

 J01FF Lincosamides

9 (2.6)

8 (2.3)

17 (2.5)

 J01CA Penicillins with extended spectrum

8 (2.3)

7 (2.0)

15 (2.2)

 J01GB Aminoglycosides

12 (3.4)

2 (0.6)

14 (2.0)

 A07AA Intestinal anti-infectives antibiotics

0 (0.0)

8 (2.3)

8 (1.1)

 J01XX09 Daptomycin

3 (0.9)

4 (1.2)

7 (1.0)

 Others

24 (6.9)

21 (6.1)

45 (6.5)

  1. Abbreviations: HAI Healthcare-Associated Infection, AMU Antimicrobial Use, ATC Anatomical Therapeutic Chemical Classification. *Percentages have been calculated on HAI prevalence in 2016 and 2018, respectively
  2. p-value = not significant; ‡ p-value < 0.05