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Table 3 Association between clinical risk factors and achieving HIV-1 DNA < 2 log10 copies/106 PBMCs

From: HIV-1 CRF01_AE subtype and HIV-1 DNA level among patients with chronic HIV-1 infection: a correlation study

VariablesUnivariateOR (95% CI)Multivariate
OR (95% CI)P-valueP-value
Sex
 Male1 1 
 Female1.758 (1.045–2.957)0.0341.447 (0.725–2.885)0.294
Age years
 18–351 1 
 36–501.439 (0.594–3.487)0.4211.328 (0.499–3.534)0.570
  > 500.850 (0.335–2.159)0.7330.801 (0.291–2.206)0.668
Transmission route
 Homosexual1 1 
 Heterosexual2.789 (1.009–7.715)0.0483.024 (0.983–9.302)0.54
 Others3.558 (1.345–9.407)0.0112.961 (1.017–8.622)0.05
HIV-1 subtype
 CRF01_AE1 1 
 Non-CRF01_AE1.554 (0.941–2.569)0.0851.279 (0.721–2.266)0.400
Baseline CD4 T cell count cells/μL
  < 2001 1 
  > 2004.903 (2.634–9.124)0.0003.341 (1.712–6.520)0.000
Baseline CD4/CD8 ratio
  < 0.51 1 
  > 0.51.948 (0.953–3.979)0.0671.475 (0.663–3.282)0.341
Baseline HIV-1 DNA log 10 copies/106 PBMCs0.380 (0.261–0.555)0.0000.489 (0.335–0.714)0.000
Baseline HIV-1 RNA log 10 copies/106 PBMCs0.758 (0.590–0.974)0.0000.985 (0.722–1.344)0.923
  1. Abbreviations: OR, Odds ratio; CI, Confidence interval; ART, Antiretroviral therapy; PBMCs, Peripheral blood mononuclear cells