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Table 1 Sociodemographic and clinical characteristics of the study population, stratified by HIV-1 subtype

From: HIV-1 CRF01_AE subtype and HIV-1 DNA level among patients with chronic HIV-1 infection: a correlation study

 Total N = 373CRF01_AE n = 188Non-CRF01_AE n = 185P-value
Sex n(%)   0.429
 Male263 (70.5)129 (68.6)134 (72.4) 
 Female110 (29.5)59 (31.4)51 (27.6) 
 Age years35 (27–43)35 (28–43)36 (27–43)0.893
Ethnic category n(%)   0.655
 Han321 (86.1)157 (83.5)164 (88.6) 
 Minority52 (13.9)31 (16.5)21 (11.4) 
Route of Transmission n(%)   0.002
MSM120 (32.2)65 (34.6)55 (29.7) 
Heterosexual195 (52.3)106 (56.4)89 (48.1) 
Others58 (15.5)17 (9.0)41 (22.2) 
Time between diagnosis and ART initiation (years)0.26 (0.99–1.18)0.32 (0.11–1.57)0.22 (0.09–0.97)0.245
Baseline HIV-1 DNA log10 copies/mL3.0 (2.6–3.4)3.19 (2.7–3.5)2.95 (2.6–3.2)0.000
Baseline plasma viral load log10 copies/mL4.6 (4.2–5.1)4.83 (4.4–5.2)4.49 (3.8–4.9)0.000
Baseline CD4+ T cell count cells/μL214 (129–299)193 (103–286)246 (157–206)0.001
Baseline CD8+ T-cell count cells/μL788 (530–1080)733 (526–1058)835 (545–1113)0.391
Baseline CD4/CD8 ratio0.24 (0.15–0.37)0.23 (0.11–0.35)0.27 (0.18–0.41)0.006
96-week HIV-1 DNA log10 copies/mL2.53 (2.09–2.91)2.63 (2.21–2.97)2.39 (2.00–2.80)0.002
  1. Continuous variables are expressed as median (interquartile range). Abbreviations: ART, Antiretroviral therapy; PBMCs, Peripheral blood mononuclear cells