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Table 1 Clinical characteristicsa) of the patient population at admissionb)

From: Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria

 

HIV only

Malaria only

Malaria and HIV

N

58

61

70

Age, years

39 (22–84)

40 (18–79)

40 (20–65)

Sex, females (%)

50 (29/58)

41 (25/61)

50 (35/70)

Hemoglobin (g/dL)

8.9 (2.9–15.2)

11.2 (3.2–17.0)

9.4 (2.5–15.7)

Leukocytes (× 109/L)

8.2 (0.3–25.4)

6.9 (1.3–15.5)

7.8 (0.9–21.8)

Platelets (×109/L)

220 (13–682)

124 (11–452)

90 (8–330)

Se-Creatinine (μmol/L)

161 (41–873)

127 (57–357)

223 (62–1529)

Se-Glucose (mmol/L)

6.1 (3.3–10.6)

8.7 (3.6–40.5)

6.12 (1.5–27.0)

Liver failure (%)c)

5 (4/57)

5 (3/61)

17 (12/70)

Coagulation disturb. (%)d)

0

2 (1/61)

13 (9/70)

Cerebral affection (%) e)

33 (19/58)

25 (15/61)

31 (22/70)

Systolic blood pressure

115 (90–160)

122 (70–240)

115 (80–170)

Respiratory rate

29 (12–56)

22 (12–68)

24 (16–42)

CD4 T-cells (106/l)f)

120 (10–196)

0

221 (14–632)

HIV-RNA (copies/ml)

2.6 × 104 (0–5.1 × 105)

0

4.2 × 104 (0–8.3 × 105)

ART before admission

29 (17/58)

0

19 (13/70)

Effective ARTg)

17 (10/58)

0

13 (9/70)

Case fatality rate (%)

27.8 (15/54)

1.7 (1/59)

13.0h) (9/69)

  1. a) Values in mean (min-max) or percentage and proportion. b) The 52 healthy controls are not included. c) Defined as jaundice/ bilirubine> 50 μmol/L d) Defined as bleeding disturbances/ hemolysis e) Defined as GCS ≤ 11, convulsions or confusion f)CD4 T-cell count were only obtained in 8 (HIV only) and 11 (HIV + malaria) patients. g) Effective ART is defined as undetectable HIV-RNA levels. h) One patient died of non-malarial cause, he was excluded