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Fig. 5 | BMC Infectious Diseases

Fig. 5

From: Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria

Fig. 5

Effects of hemozoin on IL-27Rα and gp130 gene expression in HAoEC and PBMC. The cells were incubated with different concentrations of hemozoin (Hz) ranging from 10 to 200 μg/mL (indicated as Hz10, Hz50, Hz100 and Hz200) for five (a) and 22 (b-d) hours. Gene expression analyses were done by qPCR, related to reference gene β-actin/TaqMan reference probes and normalized to unstimulated cells (US). The figure shows mRNA levels of IL-27Rα and gp130 in HAoEC (a and b) and in PBMC (c and d). Results are representatives of minimum three experiments and data are presented as mean and SEM. *p < 0.05 and **p < 0.01 versus unstimulated cells (white bar)

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BMC Infectious Diseases

ISSN: 1471-2334

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