Skip to main content
Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria

Fig. 4

Effects of IL-27 on IL-6 and IL-8 release from hemozoin-exposed peripheral blood mononuclear cells (PBMCs). PBMCs were primed with recombinant human (rh)IL-27 (100 ng/mL, 90 min) and incubated with different concentrations of hemozoin (Hz) ranging from 10 to 200 μg/mL (indicated as Hz10, Hz50, Hz100 and Hz200) for 22 h. IL-6 (a and b) and IL-8 (c and d) was measured in supernatants from the cells with EIA. Data are presented as mean and SEM of three (IL-6 data) and five (IL-8 data) separate experiments. ***p < 0.001 versus unstimulated (US) cells (white bar), and †p < 0.05 and ††p < 0.01 versus Hz (blue bar)

Back to article page