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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria

Fig. 3

Effects of IL-27 on IL-6 and IL-8 release from hemozoin-exposed human aortic endothelial cells (HAoECs). Endothelial cells were primed with recombinant (rh)IL-27 (100 ng/mL, 90 min) and incubated with 10 and 100 μg/mL hemozoin (Hz) (indicated as Hz10 and Hz100) for 22 h. IL-6 (a and b) and IL-8 (c and d) was measured in supernatants from the cells with EIA. Data are presented as mean and SEM of four (IL-6 data) and five (IL-8 data) separate experiments and shown as fold change from control. *p < 0.05 and ***p < 0.001 versus unstimulated cells (US) (white bar), and †p < 0.05 versus Hz (blue bar)

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