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Table 3 The bi-variable and multivariable Cox-regression analysis of the predictors of OIs among HIV-children on ART at Debre-Markos Referral Hospital, Northwest Ethiopia from January 1, 2005 to March 31, 2019 (N = 408)

From: Incidence of common opportunistic infections among HIV-infected children on ART at Debre Markos referral hospital, Northwest Ethiopia: a retrospective cohort study

VariablesEventsCensoredCHR (95% CI)AHR (95% CI)
Age (years)    
 0–4 years368611
 5–9 years631121.5 (0.98, 2.3)1.2 (0.8, 1.9)
 10–14 years30811.7 (1.03, 2.9)1.4 (0.8, 2.4)
Current status of parents
 Both alive5916011
 One or both dead701191.3 (0.9, 1.8)1.0 (0.7, 1.5)
History of OIs
 No4514811
 Yes841311.8 (1.3, 2.6)1.2 (0.8, 1.83)
Weight for age Z-score
 Normal weight5515211
 underweight741271.4 (1.0, 2.0)1.1 (0.7, 1.6)
Height for age Z-score
 Normal5614111
 Stunted731381.3 (0.9, 1.9)0.8 (0.5, 1.1)
WHO clinical stage
 Stage I and II4117611
 Stage III and IV881032.9 (2.0, 4.1)1.8 (1.2, 2.7)a
CD4 counts or %
 Above the threshold6021711
 Below the thresheold69623.3 (2.3, 4.6)1.7 (1.1, 2.6)a
Hgb level
 ≥ 10 g/dl10925711
 <  10 g/dl20221.7 (1.1, 2.8)1.0 (0.6, 1.7)
Ever taking IPT
 Yes6416211
 No651171.9 (1.3, 2.7)1.2 (0.8, 1.7)
ART adherence
 Good6525211
 Fair/poor64273.7 (2.6, 5.2)2.6 (1.8–3.8)a
Past OI prophylaxis
 Yes5120411
 No78752.8 (2.0, 4.0)1.6 (1.1, 2.4)a
  1. asignificant predictors