Skip to main content

Table 5 Baseline characteristics of postoperative infection children and control

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter   Postoperative infection (n = 279) Control (n = 5104) Total (n = 5383) P value
Age (days) Median (IQR) 832 (489,1386) 933 (548,1459.5) 929 (545,1458) 0.057^
CPB time (min) Median (IQR) 88 (66,125) 48 (36,72) 49 (36,75) < 0.001^
Aortic clamping time (min) Median (IQR) 52 (39,76) 28 (19,44) 29 (19,46) < 0.001^
Gender MALE 152 (54.48%) 2828 (55.41%) 2980 (55.36%) 0.762#
Preterm birth YES 2 (0.72%) 37 (0.72%) 39 (0.72%) > 0.999##
History of cardiac surgery YES 82 (29.39%) 673 (13.19%) 755 (14.03%) < 0.001#
BMI < 5th percentile 77 (29.84%) 748 (15.83%) 825 (16.56%) < 0.001#
5th–95th percentile 174 (67.44%) 3734 (79.03%) 3908 (78.43%)  
> 95th percentile 7 (2.71%) 243 (5.14%) 250 (5.02%)  
STS risk grade 1 61 (21.86%) 3064 (60.03%) 3125 (58.05%) < 0.001^
2 144 (51.61%) 1497 (29.33%) 1641 (30.48%)  
3 37 (13.26%) 356 (6.97%) 393 (7.3%)  
4 34 (12.19%) 182 (3.57%) 216 (4.01%)  
5 3 (1.08%) 5 (0.1%) 8 (0.15%)  
Delayed sternal closure YES 4 (1.43%) 8 (0.16%) 12 (0.22%) 0.003##
ALT < cut off value 19 (8.23%) 315 (6.53%) 334 (6.61%) < 0.001#
Normal 200 (86.58%) 4435 (91.97%) 4635 (91.73%)  
>cut off value 12 (5.19%) 72 (1.49%) 84 (1.66%)  
AST Normal 157 (65.15%) 3825 (78.13%) 3982 (77.52%) < 0.001#
>cut off value 84 (34.85%) 1071 (21.88%) 1155 (22.48%)  
ALP Normal 240 (99.59%) 4860 (99.31%) 5100 (99.32%) > 0.999##
>cut off value 1 (0.41%) 34 (0.69%) 35 (0.68%)  
Serum creatinine < cut off value 0 (0%) 4 (0.08%) 4 (0.08%) 0.145##
Normal 239 (99.58%) 4885 (99.88%) 5124 (99.86%)  
>cut off value 1 (0.42%) 2 (0.04%) 3 (0.06%)  
WBC counts < cut off value 4 (1.43%) 30 (0.59%) 34 (0.63%) 0.008#
Normal 263 (94.27%) 4970 (97.37%) 5233 (97.21%)  
>cut off value 12 (4.3%) 104 (2.04%) 116 (2.15%)  
Lymphocyte count < cut off value 7 (2.51%) 26 (0.51%) 33 (0.61%) < 0.001#
Normal 101 (36.2%) 1537 (30.11%) 1638 (30.43%)  
>cut off value 171 (61.29%) 3541 (69.38%) 3712 (68.96%)  
Neutrophil count < cut off value 22 (7.89%) 445 (8.72%) 467 (8.68%) 0.003#
Normal 223 (79.93%) 4311 (84.46%) 4534 (84.23%)  
>cut off value 34 (12.19%) 348 (6.82%) 382 (7.1%)  
Lymphocytes/WBC < cut off value 11 (3.94%) 49 (0.96%) 60 (1.11%) < 0.001#
Normal 63 (22.58%) 910 (17.83%) 973 (18.08%)  
>cut off value 205 (73.48%) 4145 (81.21%) 4350 (80.81%)  
Neutrophils/WBC < cut off value 209 (74.91%) 4053 (79.41%) 4262 (79.18%) 0.003#
Normal 59 (21.15%) 976 (19.12%) 1035 (19.23%)  
>cut off value 11 (3.94%) 75 (1.47%) 86 (1.6%)  
  1. Note:^ Mann-Whitney U test; ^^ T test; # Chi-square test; ## Fisher exact method
  2. CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell