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Table 5 Baseline characteristics of postoperative infection children and control

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter Postoperative infection (n = 279)Control (n = 5104)Total (n = 5383)P value
Age (days)Median (IQR)832 (489,1386)933 (548,1459.5)929 (545,1458)0.057^
CPB time (min)Median (IQR)88 (66,125)48 (36,72)49 (36,75)< 0.001^
Aortic clamping time (min)Median (IQR)52 (39,76)28 (19,44)29 (19,46)< 0.001^
GenderMALE152 (54.48%)2828 (55.41%)2980 (55.36%)0.762#
Preterm birthYES2 (0.72%)37 (0.72%)39 (0.72%)> 0.999##
History of cardiac surgeryYES82 (29.39%)673 (13.19%)755 (14.03%)< 0.001#
BMI< 5th percentile77 (29.84%)748 (15.83%)825 (16.56%)< 0.001#
5th–95th percentile174 (67.44%)3734 (79.03%)3908 (78.43%) 
> 95th percentile7 (2.71%)243 (5.14%)250 (5.02%) 
STS risk grade161 (21.86%)3064 (60.03%)3125 (58.05%)< 0.001^
2144 (51.61%)1497 (29.33%)1641 (30.48%) 
337 (13.26%)356 (6.97%)393 (7.3%) 
434 (12.19%)182 (3.57%)216 (4.01%) 
53 (1.08%)5 (0.1%)8 (0.15%) 
Delayed sternal closureYES4 (1.43%)8 (0.16%)12 (0.22%)0.003##
ALT< cut off value19 (8.23%)315 (6.53%)334 (6.61%)< 0.001#
Normal200 (86.58%)4435 (91.97%)4635 (91.73%) 
>cut off value12 (5.19%)72 (1.49%)84 (1.66%) 
ASTNormal157 (65.15%)3825 (78.13%)3982 (77.52%)< 0.001#
>cut off value84 (34.85%)1071 (21.88%)1155 (22.48%) 
ALPNormal240 (99.59%)4860 (99.31%)5100 (99.32%)> 0.999##
>cut off value1 (0.41%)34 (0.69%)35 (0.68%) 
Serum creatinine< cut off value0 (0%)4 (0.08%)4 (0.08%)0.145##
Normal239 (99.58%)4885 (99.88%)5124 (99.86%) 
>cut off value1 (0.42%)2 (0.04%)3 (0.06%) 
WBC counts< cut off value4 (1.43%)30 (0.59%)34 (0.63%)0.008#
Normal263 (94.27%)4970 (97.37%)5233 (97.21%) 
>cut off value12 (4.3%)104 (2.04%)116 (2.15%) 
Lymphocyte count< cut off value7 (2.51%)26 (0.51%)33 (0.61%)< 0.001#
Normal101 (36.2%)1537 (30.11%)1638 (30.43%) 
>cut off value171 (61.29%)3541 (69.38%)3712 (68.96%) 
Neutrophil count< cut off value22 (7.89%)445 (8.72%)467 (8.68%)0.003#
Normal223 (79.93%)4311 (84.46%)4534 (84.23%) 
>cut off value34 (12.19%)348 (6.82%)382 (7.1%) 
Lymphocytes/WBC< cut off value11 (3.94%)49 (0.96%)60 (1.11%)< 0.001#
Normal63 (22.58%)910 (17.83%)973 (18.08%) 
>cut off value205 (73.48%)4145 (81.21%)4350 (80.81%) 
Neutrophils/WBC< cut off value209 (74.91%)4053 (79.41%)4262 (79.18%)0.003#
Normal59 (21.15%)976 (19.12%)1035 (19.23%) 
>cut off value11 (3.94%)75 (1.47%)86 (1.6%) 
  1. Note:^ Mann-Whitney U test; ^^ T test; # Chi-square test; ## Fisher exact method
  2. CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell