Skip to main content

Table 4 Univariate and multivariate logistic regression analysis of risk factors for postoperative infection in infants with congenital heart disease

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter Univariate analysisMultivariate analysis
OR (95% CI)P-valueOR (95% CI)P value
Age (days)Unit = 300.812 (0.789,0.835)< 0.0010.798 (0.769,0.829)< 0.001
GenderFemale1.000   
Male1.1 (0.956,1.265)0.184  
Preterm birthNo1.000   
Yes0.854 (0.384,1.899)0.698  
History of cardiac surgeryNo1.000   
Yes1.235 (0.674,2.262)0.495  
STS risk gradeUnit = 11.625 (1.517,1.74)< 0.0011.267 (1.159,1.385)< 0.001
Delayed sternal closureNo1.000   
Yes6.235 (2.4,16.203)< 0.001  
BMI5th–95th percentile1.000   
< 5th percentile0.769 (0.632,0.936)0.0091.295 (1.023,1.639)0.032
> 95th percentile1.054 (0.886,1.254)0.5520.792 (0.647,0.969)0.023
CPB timeUnit = 11.017 (1.015,1.019)< 0.0011.008 (1.003,1.012)< 0.001
Aortic clamping timeUnit = 11.023 (1.02,1.026)< 0.0011.009 (1.002,1.015)0.008
Lymphocyte countNormal1.000   
< cut off value0.938 (0.626,1.405)0.756  
>cut off value0.757 (0.646,0.886)0.001  
Lymphocytes /WBCNormal1.000   
< cut off value1.938 (1.442,2.605)< 0.001  
>cut off value0.652 (0.561,0.757)< 0.001  
Neutrophil countNormal1.000   
< cut off value0.919 (0.781,1.081)0.308  
>cut off value1.503 (1.078,2.097)0.016  
Neutrophil /WBCNormal1.000   
< cut off value0.766 (0.64,0.918)0.0040.838 (0.676,1.039)0.107
>cut off value1.664 (1.314,2.106)< 0.0011.264 (0.939,1.7)0.122
ALTNormal1.000   
< cut off value1.461 (0.88,2.425)0.143  
>cut off value1.142 (0.874,1.492)0.329  
ASTNormal1.000   
>cut off value0.994 (0.855,1.157)0.943  
ALPNormal1.000   
>cut off value1.4 (0.613,3.196)0.425  
Serum creatinineNormal1.000   
< cut off value1.136 (0.505,2.557)0.758  
>cut off value18.008 (1.871,173.3)0.012  
  1. Note: CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell