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Table 4 Univariate and multivariate logistic regression analysis of risk factors for postoperative infection in infants with congenital heart disease

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter

 

Univariate analysis

Multivariate analysis

OR (95% CI)

P-value

OR (95% CI)

P value

Age (days)

Unit = 30

0.812 (0.789,0.835)

< 0.001

0.798 (0.769,0.829)

< 0.001

Gender

Female

1.000

   

Male

1.1 (0.956,1.265)

0.184

  

Preterm birth

No

1.000

   

Yes

0.854 (0.384,1.899)

0.698

  

History of cardiac surgery

No

1.000

   

Yes

1.235 (0.674,2.262)

0.495

  

STS risk grade

Unit = 1

1.625 (1.517,1.74)

< 0.001

1.267 (1.159,1.385)

< 0.001

Delayed sternal closure

No

1.000

   

Yes

6.235 (2.4,16.203)

< 0.001

  

BMI

5th–95th percentile

1.000

   

< 5th percentile

0.769 (0.632,0.936)

0.009

1.295 (1.023,1.639)

0.032

> 95th percentile

1.054 (0.886,1.254)

0.552

0.792 (0.647,0.969)

0.023

CPB time

Unit = 1

1.017 (1.015,1.019)

< 0.001

1.008 (1.003,1.012)

< 0.001

Aortic clamping time

Unit = 1

1.023 (1.02,1.026)

< 0.001

1.009 (1.002,1.015)

0.008

Lymphocyte count

Normal

1.000

   

< cut off value

0.938 (0.626,1.405)

0.756

  

>cut off value

0.757 (0.646,0.886)

0.001

  

Lymphocytes /WBC

Normal

1.000

   

< cut off value

1.938 (1.442,2.605)

< 0.001

  

>cut off value

0.652 (0.561,0.757)

< 0.001

  

Neutrophil count

Normal

1.000

   

< cut off value

0.919 (0.781,1.081)

0.308

  

>cut off value

1.503 (1.078,2.097)

0.016

  

Neutrophil /WBC

Normal

1.000

   

< cut off value

0.766 (0.64,0.918)

0.004

0.838 (0.676,1.039)

0.107

>cut off value

1.664 (1.314,2.106)

< 0.001

1.264 (0.939,1.7)

0.122

ALT

Normal

1.000

   

< cut off value

1.461 (0.88,2.425)

0.143

  

>cut off value

1.142 (0.874,1.492)

0.329

  

AST

Normal

1.000

   

>cut off value

0.994 (0.855,1.157)

0.943

  

ALP

Normal

1.000

   

>cut off value

1.4 (0.613,3.196)

0.425

  

Serum creatinine

Normal

1.000

   

< cut off value

1.136 (0.505,2.557)

0.758

  

>cut off value

18.008 (1.871,173.3)

0.012

  
  1. Note: CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell