From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease
Parameter | Postoperative Infection (n = 952) | Control (n = 5231) | Total (n = 6183) | P value | |
---|---|---|---|---|---|
Age (days) | Median (IQR) | 138 (87.5208) | 196 (130,255) | 188 (122,250) | < 0.001^ |
CPB time (min) | Median (IQR) | 69 (51,98) | 51 (40,70) | 54 (41,74) | < 0.001^ |
Aortic clamping time (min) | Median (IQR) | 42 (28,61) | 31 (23,43) | 32 (23,46) | < 0.001^ |
Gender | MALE | 564 (59.24%) | 2978 (56.93%) | 3542 (57.29%) | 0.184# |
Preterm birth | YES | 7 (0.74%) | 45 (0.86%) | 52 (0.84%) | 0.698# |
History of cardiac surgery | YES | 13 (1.37%) | 58 (1.11%) | 71 (1.15%) | 0.494# |
BMI | < 5th percentile | 148 (16.95%) | 1040 (21.24%) | 1188 (20.59%) | 0.013# |
5th~95th percentile | 508 (58.19%) | 2744 (56.05%) | 3252 (56.37%) | ||
> 95th percentile | 217 (24.86%) | 1112 (22.71%) | 1329 (23.04%) | ||
STS risk grade | 1 | 366 (38.45%) | 3150 (60.22%) | 3516 (56.87%) | < 0.001^ |
2 | 310 (32.56%) | 1443 (27.59%) | 1753 (28.35%) | ||
3 | 158 (16.6%) | 332 (6.35%) | 490 (7.92%) | ||
4 | 116 (12.18%) | 304 (5.81%) | 420 (6.79%) | ||
5 | 2 (0.21%) | 2 (0.04%) | 4 (0.06%) | ||
Delayed sternal closure | YES | 9 (0.95%) | 8 (0.15%) | 17 (0.27%) | < 0.001## |
ALT | < cut off value | 19 (2.3%) | 79 (1.6%) | 98 (1.7%) | 0.224# |
Normal | 737 (89.23%) | 4473 (90.84%) | 5210 (90.61%) | ||
>cut off value | 70 (8.47%) | 372 (7.55%) | 442 (7.69%) | ||
AST | Normal | 316 (38.16%) | 1880 (38.03%) | 2196 (38.05%) | 0.943# |
>cut off value | 512 (61.84%) | 3063 (61.97%) | 3575 (61.95%) | ||
ALP | Normal | 819 (99.15%) | 4910 (99.39%) | 5729 (99.36%) | 0.424# |
>cut off value | 7 (0.85%) | 30 (0.61%) | 37 (0.64%) | ||
Serum creatinine | < cut off value | 7 (0.85%) | 37 (0.75%) | 44 (0.77%) | 0.013## |
Normal | 814 (98.79%) | 4888 (99.23%) | 5702 (99.17%) | ||
>cut off value | 3 (0.36%) | 1 (0.02%) | 4 (0.07%) | ||
WBC counts | < cut off value | 18 (1.89%) | 55 (1.05%) | 73 (1.18%) | 0.075# |
Normal | 898 (94.33%) | 4956 (94.74%) | 5854 (94.68%) | ||
>cut off value | 36 (3.78%) | 220 (4.21%) | 256 (4.14%) | ||
Lymphocyte count | < cut off value | 32 (3.36%) | 153 (2.92%) | 185 (2.99%) | 0.002# |
Normal | 260 (27.31%) | 1166 (22.29%) | 1426 (23.06%) | ||
>cut off value | 660 (69.33%) | 3912 (74.78%) | 4572 (73.94%) | ||
Neutrophil count | < cut off value | 228 (23.95%) | 1357 (25.94%) | 1585 (25.63%) | 0.022# |
Normal | 677 (71.11%) | 3703 (70.79%) | 4380 (70.84%) | ||
>cut off value | 47 (4.94%) | 171 (3.27%) | 218 (3.53%) | ||
Lymphocytes/WBC | < cut off value | 76 (7.98%) | 170 (3.25%) | 246 (3.98%) | < 0.001# |
Normal | 331 (34.77%) | 1435 (27.43%) | 1766 (28.56%) | ||
>cut off value | 545 (57.25%) | 3626 (69.32%) | 4171 (67.46%) | ||
Neutrophils/WBC | < cut off value | 599 (62.92%) | 3831 (73.24%) | 4430 (71.65%) | < 0.001# |
Normal | 184 (19.33%) | 902 (17.24%) | 1086 (17.56%) | ||
>cut off value | 169 (17.75%) | 498 (9.52%) | 667 (10.79%) |