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Table 3 Baseline characteristics of postoperative infection infants and control

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter Postoperative Infection (n = 952)Control (n = 5231)Total (n = 6183)P value
Age (days)Median (IQR)138 (87.5208)196 (130,255)188 (122,250)< 0.001^
CPB time (min)Median (IQR)69 (51,98)51 (40,70)54 (41,74)< 0.001^
Aortic clamping time (min)Median (IQR)42 (28,61)31 (23,43)32 (23,46)< 0.001^
GenderMALE564 (59.24%)2978 (56.93%)3542 (57.29%)0.184#
Preterm birthYES7 (0.74%)45 (0.86%)52 (0.84%)0.698#
History of cardiac surgeryYES13 (1.37%)58 (1.11%)71 (1.15%)0.494#
BMI< 5th percentile148 (16.95%)1040 (21.24%)1188 (20.59%)0.013#
5th~95th percentile508 (58.19%)2744 (56.05%)3252 (56.37%) 
> 95th percentile217 (24.86%)1112 (22.71%)1329 (23.04%) 
STS risk grade1366 (38.45%)3150 (60.22%)3516 (56.87%)< 0.001^
2310 (32.56%)1443 (27.59%)1753 (28.35%) 
3158 (16.6%)332 (6.35%)490 (7.92%) 
4116 (12.18%)304 (5.81%)420 (6.79%) 
52 (0.21%)2 (0.04%)4 (0.06%) 
Delayed sternal closureYES9 (0.95%)8 (0.15%)17 (0.27%)< 0.001##
ALT< cut off value19 (2.3%)79 (1.6%)98 (1.7%)0.224#
Normal737 (89.23%)4473 (90.84%)5210 (90.61%) 
>cut off value70 (8.47%)372 (7.55%)442 (7.69%) 
ASTNormal316 (38.16%)1880 (38.03%)2196 (38.05%)0.943#
>cut off value512 (61.84%)3063 (61.97%)3575 (61.95%) 
ALPNormal819 (99.15%)4910 (99.39%)5729 (99.36%)0.424#
>cut off value7 (0.85%)30 (0.61%)37 (0.64%) 
Serum creatinine< cut off value7 (0.85%)37 (0.75%)44 (0.77%)0.013##
Normal814 (98.79%)4888 (99.23%)5702 (99.17%) 
>cut off value3 (0.36%)1 (0.02%)4 (0.07%) 
WBC counts< cut off value18 (1.89%)55 (1.05%)73 (1.18%)0.075#
Normal898 (94.33%)4956 (94.74%)5854 (94.68%) 
>cut off value36 (3.78%)220 (4.21%)256 (4.14%) 
Lymphocyte count< cut off value32 (3.36%)153 (2.92%)185 (2.99%)0.002#
Normal260 (27.31%)1166 (22.29%)1426 (23.06%) 
>cut off value660 (69.33%)3912 (74.78%)4572 (73.94%) 
Neutrophil count< cut off value228 (23.95%)1357 (25.94%)1585 (25.63%)0.022#
Normal677 (71.11%)3703 (70.79%)4380 (70.84%) 
>cut off value47 (4.94%)171 (3.27%)218 (3.53%) 
Lymphocytes/WBC< cut off value76 (7.98%)170 (3.25%)246 (3.98%)< 0.001#
Normal331 (34.77%)1435 (27.43%)1766 (28.56%) 
>cut off value545 (57.25%)3626 (69.32%)4171 (67.46%) 
Neutrophils/WBC< cut off value599 (62.92%)3831 (73.24%)4430 (71.65%)< 0.001#
Normal184 (19.33%)902 (17.24%)1086 (17.56%) 
>cut off value169 (17.75%)498 (9.52%)667 (10.79%) 
  1. Note:^ Mann-Whitney U test; ^^ T test; # Chi-square test; ## Fisher exact method
  2. CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell