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Table 3 Baseline characteristics of postoperative infection infants and control

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter

 

Postoperative Infection (n = 952)

Control (n = 5231)

Total (n = 6183)

P value

Age (days)

Median (IQR)

138 (87.5208)

196 (130,255)

188 (122,250)

< 0.001^

CPB time (min)

Median (IQR)

69 (51,98)

51 (40,70)

54 (41,74)

< 0.001^

Aortic clamping time (min)

Median (IQR)

42 (28,61)

31 (23,43)

32 (23,46)

< 0.001^

Gender

MALE

564 (59.24%)

2978 (56.93%)

3542 (57.29%)

0.184#

Preterm birth

YES

7 (0.74%)

45 (0.86%)

52 (0.84%)

0.698#

History of cardiac surgery

YES

13 (1.37%)

58 (1.11%)

71 (1.15%)

0.494#

BMI

< 5th percentile

148 (16.95%)

1040 (21.24%)

1188 (20.59%)

0.013#

5th~95th percentile

508 (58.19%)

2744 (56.05%)

3252 (56.37%)

 

> 95th percentile

217 (24.86%)

1112 (22.71%)

1329 (23.04%)

 

STS risk grade

1

366 (38.45%)

3150 (60.22%)

3516 (56.87%)

< 0.001^

2

310 (32.56%)

1443 (27.59%)

1753 (28.35%)

 

3

158 (16.6%)

332 (6.35%)

490 (7.92%)

 

4

116 (12.18%)

304 (5.81%)

420 (6.79%)

 

5

2 (0.21%)

2 (0.04%)

4 (0.06%)

 

Delayed sternal closure

YES

9 (0.95%)

8 (0.15%)

17 (0.27%)

< 0.001##

ALT

< cut off value

19 (2.3%)

79 (1.6%)

98 (1.7%)

0.224#

Normal

737 (89.23%)

4473 (90.84%)

5210 (90.61%)

 

>cut off value

70 (8.47%)

372 (7.55%)

442 (7.69%)

 

AST

Normal

316 (38.16%)

1880 (38.03%)

2196 (38.05%)

0.943#

>cut off value

512 (61.84%)

3063 (61.97%)

3575 (61.95%)

 

ALP

Normal

819 (99.15%)

4910 (99.39%)

5729 (99.36%)

0.424#

>cut off value

7 (0.85%)

30 (0.61%)

37 (0.64%)

 

Serum creatinine

< cut off value

7 (0.85%)

37 (0.75%)

44 (0.77%)

0.013##

Normal

814 (98.79%)

4888 (99.23%)

5702 (99.17%)

 

>cut off value

3 (0.36%)

1 (0.02%)

4 (0.07%)

 

WBC counts

< cut off value

18 (1.89%)

55 (1.05%)

73 (1.18%)

0.075#

Normal

898 (94.33%)

4956 (94.74%)

5854 (94.68%)

 

>cut off value

36 (3.78%)

220 (4.21%)

256 (4.14%)

 

Lymphocyte count

< cut off value

32 (3.36%)

153 (2.92%)

185 (2.99%)

0.002#

Normal

260 (27.31%)

1166 (22.29%)

1426 (23.06%)

 

>cut off value

660 (69.33%)

3912 (74.78%)

4572 (73.94%)

 

Neutrophil count

< cut off value

228 (23.95%)

1357 (25.94%)

1585 (25.63%)

0.022#

Normal

677 (71.11%)

3703 (70.79%)

4380 (70.84%)

 

>cut off value

47 (4.94%)

171 (3.27%)

218 (3.53%)

 

Lymphocytes/WBC

< cut off value

76 (7.98%)

170 (3.25%)

246 (3.98%)

< 0.001#

Normal

331 (34.77%)

1435 (27.43%)

1766 (28.56%)

 

>cut off value

545 (57.25%)

3626 (69.32%)

4171 (67.46%)

 

Neutrophils/WBC

< cut off value

599 (62.92%)

3831 (73.24%)

4430 (71.65%)

< 0.001#

Normal

184 (19.33%)

902 (17.24%)

1086 (17.56%)

 

>cut off value

169 (17.75%)

498 (9.52%)

667 (10.79%)

 
  1. Note:^ Mann-Whitney U test; ^^ T test; # Chi-square test; ## Fisher exact method
  2. CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell