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Table 4 The analysis of the relevant factors of pathogens DNA positive in patients

From: The diagnostic value of metagenomic next⁃generation sequencing in infectious diseases

Values

B

SE (B)

Wald X2

P

OR

95% CI

Age

0.073

0.035

4.367

0.037

1.076

1.005–1.152

Sex

−0.545

1.157

0.222

0.637

0.58

0.06–5.601

Read Number

−2.371

0.599

15.677

0.000

0.093

0.029–0.302

HOD

−0.028

0.061

0.216

0.642

0.972

0.863–1.095

Survival Time

−0.007

0.005

1.888

0.169

0.993

0.983–1.003

Cytokines pg/ml

 IL-2

0.171

1.115

0.023

0.878

1.186

0.133–10.553

 IL-4

−1.299

0.893

2.116

0.146

0.273

0.047–1.57

 IL-6

−0.005

0.019

0.077

0.781

0.995

0.957–1.033

 TNF-α

−0.374

0.373

1.003

0.316

0.688

0.331–1.430

 IL-17a

0.202

0.137

2.165

0.141

1.223

0.935–1.6

 IL-10

−2.64

0.206

1.639

0.201

0.768

0.513–1.151

 IFN-γ

0.09

0.071

1.606

0.205

1.095

0.952–1.259

Cellular Immunity %

 CD4/CD8

−0.488

0.965

0.256

0.613

0.614

0.093–4.067

 Th cell

0.318

0.296

1.151

0.283

1.374

0.769–2.454

 Ts cell

0.244

0.317

0.589

0.443

1.276

0.685–2.377

 NK cell

−0.223

0.211

1.121

0.29

0.800

0.529–1.209

 B cell

−0.26-

0.245

1.172

0.279

0.767

0.227–1.475

 T cell

0.5485

0.478

1.315

0.252

0.578

0.475–1.239

 WBC ×109

−0.123

1.228

0.01

0.92

0.884

0.08–9.819

 Neu×109

0.141

1.39

0.01

0.919

1.151

0.076–17.535

 PCT ng/ml

−0.681

1.514

0.202

0.653

0.506

0.026–9.844

 CRP mg/l

−0.004

0.015

0.073

0.788

0.996

0.968–1.025

  1. Abbreviations: HOD hospital day, WBC white blood cells, IL- interleukin-, IFN-γ Interferon-γ, TNF-α Tumor Necrosis Factor-α, CD4 Cluster of Differentiation 4 receptors, CD8 Cluster of Differentiation 8 receptors, Th helper T cell, Ts suppressor T cell, NK natural killer cell, Neu neutrophil, PCT procalcitonin, CRP C-reactive protein