Skip to main content

Table 3 The counts of WBC, Cytokines and lymphocytes in positive and negative groups by mNGS

From: The diagnostic value of metagenomic next⁃generation sequencing in infectious diseases

 

Positive

Negative

P

Cytokines pg/ml

 IL-2

100.35 + 68.21

1.31 + 0.94

0.511

 IL-4

2.74 + 0.41

1.52 + 0.94

0.206

 IL-6

70.8 + 18.27

68.96 + 33.18

0.964

 TNF-α

2.48 + 0.42

2.26 + 1.32

0.842

 IL-17a

13.77 + 2.35

10.45 + 8.01

0.592

 IL-8

1154 + 0

 IL-10

26.14 + 7.75

8.29 + 3.33

0.044

 IFN-γ

8.91 + 1.89

13.59 + 6.92

0.361

Cellular Immunity %

 CD4/CD8

1.42 + 0.23

2.06 + 0.44

0.185

 Th cell

35 + 3.36

43.83 + 5.75

0.201

 Ts cell

68.06 + 3.07

66.67 + 3.64

0.18

 NK cell

15.71 + 2.17

15.5 + 1.89

0.958

 B cell

13.53 + 2.94

12.83 + 3.73

0.899

 T cell

68.06 + 3.07

66.67 + 3.64

0.958

 WBC ×109

8.32 + 0.52

7.36 + 0.48

0.283

 Neu× 109

6.99 + 0.58

5.38 + 0.48

0.109

 PCT ng/ml

0.34 + 0.17

3.42 + 3.32

0.112

 CRP mg/l

87.63 + 8.32

63.61 + 13.47

0.129

  1. Abbreviations: mNGS metagenomic next-generation sequencing, WBC white blood cells, IL- interleukin-, IFN-γ Interferon-γ, TNF-α Tumor Necrosis Factor-α, CD4 Cluster of Differentiation 4 receptors, CD8 Cluster of Differentiation 8 receptors, Th helper T cell, Ts suppressor T cell, NK natural killer cell, Neu neutrophil, PCT procalcitonin, CRP C-reactive protein