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Table 4 A-B Comparison of G12P[6] strains with reference P[6] strains representing the four P[6] lineages within the VP8* antigenic regions [47, 50]. Amino acids substitutions within the studied strains are bolded and * indicates the amino acid is conserved

From: Genetic characterization of G12P[6] and G12P[8] rotavirus strains collected in six African countries between 2010 and 2014

A P[6] Lineage Country (Year) of isolation 8–1 8–2 8–3
100 146 148 150 188 190 192 193 194 195 180 183 113 114 115 116 125 131
305 I Iran (2017) D S S E S T N L S E T A T N Q S T E
Gottrified II USA (1975) * N N D * * * * P D * * P S * D V *
JP3–6 III Japan * N * * * * * * Y D * * V S * * * *
B1198 IV Hungary (1998) * N * * * * * * * * * * * * * * * *
MRC-DPRU1765 I Zambia (2012) * * * * * * * * * * * * * * * * * *
MRC-DPRU1369 I Kenya (2012) * N * * * * * * * * * * * * * * * *
#MRC-DPR857 I Ethiopia (2012) * * * * * * * * * * * * * * * * * *
B P[6] Lineage Country (Year) of isolation 8–3 8–4             
132 133 135 87 88 89             
305 I Iran (2017) N N N T N Q             
Gottrified II USA (1975) * S D I * K             
JP3–6 III Japan * * * * * *             
B1198 IV Hungary (1998) * S * * * *             
MRC-DPRU1765 I Zambia (2012) * * * * * *             
MRC-DPRU1369 I Kenya (2012) * * * * * *             
MRC-DPR857 I Ethiopia (2012) * * * * * *             
  1. #Strain represents itself
  2. MRC-DPRU1765 represent one other strain from Zambia
  3. MRC-DPRU1369 represent three other strains from Kenya