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Table 2 Results of multivariate Cox proportional-hazards regression analyzing the effect of baseline variables on in-hospital death in all patients with COVID-19

From: Clinical characteristics and predictive value of lower CD4+T cell level in patients with moderate and severe COVID-19: a multicenter retrospective study

Mode

HR (95%CI)

P

Not adjusted CD4+T level, lower vs. higher

13.659 (3.235–57.671)

< 0.001

Mode 1

 CD4+T cell level, lower vs. higher

14.182 (1.884–106.786)

0.010

 Sex, male vs. female

1.383 (0.561–3.406)

0.481

 Age, per 1 year

1.093 (1.052–1.135)

< 0.001

 Temperature, per 1 °C

0.777 (0.445–1.354)

0.372

Mode 2

 CD4+T cell level, lower vs. higher

13.631 (3.190–58.243)

< 0.001

 Hypertension, yes vs. no

5.823 (2.595–13.070)

< 0.001

 Diabetes, yes vs. no

0.824 (0.322–2.113)

0.688

 Shortness of breath, yes vs. no

7.848 (2.942–20.934)

< 0.001

Mode 3

 CD4+T cell level, lower vs. higher

8.170 (1.877–35.566)

0.005

 WBC, per 1×109/L

1.294 (1.193–1.404)

< 0.001

 PLT, per 1×109/L

0.992 (0.987–0.997)

0.003

 Cr, per 1 umol/L

1.002 (0.995–1.009)

0.576

Mode 4

 CD4+T cell level, lower vs. higher

10.644 (2.439–46.458)

0.002

 Hs-CRP, per 1 mg/L

0.989 (0.974–1.005)

0.193

 PCT, per 1 ng/ml

1.017 (0.925–1.118)

0.724

 D-dimer, per 1 mg/L

1.028 (1.018–1.038)

< 0.001

Mode 5

 CD4+T cell level, lower vs. higher

13.650 (1.976–94.279)

0.008

 CD8+T cell level, lower vs. higher

3.159 (0.853–11.707)

0.085

 CD4/CD8 ratio, per 1 unit

1.422 (1.105–1.830)

0.006

 LYM level, lower vs. higher

0.996 (0.306–3.243)

0.994

Mode 6

 CD4+T cell level, lower vs. higher

7.656 (1.610–36.396)

0.010

 Age, per 1 year

1.074 (1.034–1.115)

< 0.001

 Hypertension, yes vs. no

2.031 (0.766–5.386)

0.154

 Shortness of breath, yes vs. no

3.435 (1.167–10.114)

0.025

 WBC, per 1×109/L

1.224 (1.097–1.366)

< 0.001

 PLT, per 1× 109/L

0.996 (0.991–1.001)

0.149

 D-dimer, per 1 mg/L

0.997 (0.992–1.002)

0.207

 CD4/CD8 ratio, per 1 unit

1.106 (0.793–1.542)

0.552

  1. Abbreviations: WBC white blood cell, PLT platelet, Cr creatinine, Hs-CRP hypersensitive C-reactive protein, PCT procalcitonin, LYM lymphocyte