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Table 2 Antibody titers in patients who had recovered from scrub typhus (N = 91) based on IgM and IgG positivity at several timepoints, as determined by the IFA used by the KCDC

From: Follow-up investigation of antibody titers and diagnostic antibody cutoff values in patients with scrub typhus in South Korea

IFA of KCDC

1 year

2 years

3 years

4 years

5 years

6 years

7 years

8 years

9 years

10 years

11 years

12 years

13 years

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

IgM

n

(CP)

IgG

n

(CP)

0

10

(100)

10

(100)

4

(100)

2

(100)

6

(100)

5

(100)

1

(100)

1

(100)

4

(100)

2

(100)

6

(100)

3

(100)

3

(100)

1

(100)

3

(100)

2

(100)

6

(100)

3

(100)

6

(100)

2

(100)

3

(100)

3

(100)

2

(100)

1

(100)

3

(100)

2

(100)

1:16

1

(37.5)

0

(37.5)

0

(50)

0

(75)

2

(66.7)

0

(72.2)

1

(66.7)

0

(66.7)

1

(42.9)

0

(71.4)

0

(25)

0

(62.5)

2

(40)

0

(80)

0

(0)

0

(33.3)

0

(0)

0

(50)

0

(0)

1

(66.7)

1

(50)

0

(50)

0

(0)

0

(50)

0

(0)

0

(33.3)

1:32

3

(31.3)

0

(37.5)

2

(50)

1

(75)

5

(55.6)

5

(72.2)

1

(33.3)

0

(66.7)

0

(28.6)

0

(71.5)

1

(25)

0

(62.5)

0

(0)

1

(80)

0

(0)

0

(33.3)

0

(0)

1

(50)

0

(0)

0

(50)

0

(33.3)

0

(50)

0

(0)

0

(50)

0

(0)

1

(33.3)

1:64

1

(12.5)

0

(37.5)

1

(25)

1

(62.5)

3

(27.8)

2

(44.4)

0

(0)

0

(66.7)

2

(28.6)

2

(71.4)

1

(12.5)

1

(62.5)

0

(0)

2

(60)

0

(0)

1

(33.3)

0

(0)

1

(33.3)

0

(0)

1

(50)

2

(33.3)

0

(50)

0

(0)

0

(50)

0

(0)

0

(0)

1:128

0

(6.3)

0

(37.5)

1

(12.5)

1

(50)

2

(11.1)

4

(33.3)

0

(0)

1

(66.7)

0

(0)

2

(42.9)

0

(0)

1

(50)

0

(0)

0

(20)

0

(0)

0

(0)

0

(0)

0

(16.7)

0

(0)

1

(33.3)

0

(0)

2

(50)

0

(0)

1

(50)

0

(0

0

(0)

1:256

1

(6.3)

1

(37.5)

0

(0)

2

(37.5)

0

(0)

1

(11.1)

0

(0)

1

(33.3)

0

(0)

0

(14.3)

0

(0)

2

(37.5)

0

(0)

0

(20)

0

(0)

0

(0)

0

(0)

0

(16.7)

0

(0)

1

(16.7)

0

(0)

1

(16.7)

0

(0)

0

(0)

0

(0)

0

(0)

1:512

0

(0)

1

(31.3)

0

(0)

1

(12.5)

0

(0)

1

(5.6)

0

(0)

0

(0)

0

(0)

1

(14.3)

0

(0)

1

(12.5)

0

(0)

1

(20)

0

(0)

0

(0)

0

(0)

0

(16.7)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

1:1024

0

(0)

3

(25)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

1

(16.7)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

1:2048

0

(0)

1

(6.3)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

(0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0)

(0

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

0

(0)

Total

n

16

8

18

3

7

8

5

3

6

6

6

2

3

  1. Bold indicates the results obtained at cutoff values of ≥1:16 for IgM and ≥1:256 for IgG, which are reference cutoff values for positivity
  2. CP cumulative percentage, IFA immunofluorescence assay, KCDC Korean Centers for Disease Control and Prevention