TY - JOUR AU - Yu, Yali AU - Xu, Fei AU - Shen, Hui AU - Wu, Jiang PY - 2021 DA - 2021/01/07 TI - Chronic Candida infection, bronchiectasis, immunoglobulin abnormalities, and stunting: a case report of a natural mutation of STAT1 (c.986C>G) in an adolescent male JO - BMC Infectious Diseases SP - 38 VL - 21 IS - 1 AB - Chronic mucocutaneous candidiasis (CMC) is the most common clinical symptom of singer transducer and signal transducer and activator of transcription 1 (STAT1) gain-of-function (GOF) mutations. Bronchiectasis is a chronic lung disease that is characterized by permanent bronchiectasis, causing cough, expectoration, and even haemoptysis. The underlying pathogeny is not yet clear. Immunoglobulin (Ig) A is derived from memory B cells and correlates with immune-related diseases. STAT1 is closely associated with signal transmission and immune regulation. SN - 1471-2334 UR - https://doi.org/10.1186/s12879-020-05734-9 DO - 10.1186/s12879-020-05734-9 ID - Yu2021 ER -