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Table 1 Baseline characteristics of included studies. Included studies classifications of First Author, Year, Country, Study Type, Type of JAK-inhibitor/Type I interferon Used, Total Number of Participants, Number of Participants Receiving JAK-inhibitor/Type I interferon Used. Studies presented in alphabetical order by treatment group

From: JAK-inhibitor and type I interferon ability to produce favorable clinical outcomes in COVID-19 patients: a systematic review and meta-analysis

First Author, Year

Country

Study Type

JAK-inhibitor/Interferon Used

Total # of Participants

N Participants Receiving JAK-inhibitor/Interferona

Bronte 2020 [25]

Italy

Observational

Baricitinib

76

20

Cantini 2020a [26]

Italy

Retrospective Cohort

Baricitinib

191

113

Cantini 2020b [27]

Italy

Prospective Cohort, open-label

Baricitinib

24

12

Cao 2020 [28]

China

RCT

Ruxolitinib

41

20

Giudice 2020 [29]

Italy

RCT

Ruxolitinib

17

7

Chen 2020 [30]

China

Observational

IFN-alpha-2b

291

132

Davoudi-Monfared 2020 [31]

Iran

RCT

IFN-beta-1a

81

42

Du 2020 [32]

China

Retrospective Cohort

IFN-alpha

182

178

Estébanez 2020 [33]

Spain

Retrospective Cohort

IFN-beta-1b

256

106

Fan 2020 [34]

China

Retrospective Observational

IFN-alpha-1b

53

19

Hung 2020 [35]

China

RCT

IFN-beta-1b

127

86

Liu 2020 [36]

China

Retrospective Observational

IFN-alpha-2b

10

9

Pereda 2020 [37]

Cuba

Retrospective Cohort

IFN-alpha-2b

814

761

Wang 2020 [38]

China

Retrospective Cohort

IFN-alpha-2b

446

242

Zhou 2020 [39]

China

Retrospective Cohort

IFNb

221

139

  1. IFN Interferon
  2. a No Study participants received JAK-inhibitor and Type I interferon
  3. b Unclear – Used in combination with Arbidol