Fig. 3
Forest plot of (a) Mortality, (b) ICU Admission, (c) Requirement of Mechanical Ventilation, (d) Severe or Critical Disease, and (e) Discharge of patients treated with Type I interferon. The fixed effects and random effects model was used dependent on the I2 measure of heterogeneity. Type I interferon group saw significantly reduced odds of mortality, as well as increased odds of discharge that bordered significance, when compared to standard treatment. There was no significant difference between groups in regards to requiring ICU admission, mechanical ventilation, or the development of severe or critical disease. The meta-analysis results are presented on forest plots, with a study’s calculated OR plotted as a black square whose size is proportional to the weight afforded to the study. Bidirectional bars stemming from these black squares correspond to the risk estimate’s 95% CI. Diamonds were used to represent the summary OR; its center aligns with the OR and its width represents the summary 95% CI