Fig. 2

Forest plot of (a) Mortality, (b) ICU Admission, (c) Requirement of Mechanical Ventilation, (d) ARDS, and (e) Discharge of patients treated with JAK-inhibitor. The fixed effects model was used. JAK-inhibitor treatment group saw significantly reduced odds of mortality and ICU admission, as well as significantly higher odds of discharge, when compared to standard treatment. There was no significant difference between groups in regards to requiring mechanical ventilation, or the development of ARDS. The meta-analysis results are presented on forest plots, with a study’s calculated OR plotted as a black square whose size is proportional to the weight afforded to the study. Bidirectional bars stemming from these black squares correspond to the risk estimate’s 95% CI. Diamonds were used to represent the summary OR; its center aligns with the OR and its width represents the summary 95% CI