Table 2 Sensitivity and Specificity of Sputum Xpert Ultra by HIV status and prior history of TB, in Kampala, Uganda

Total Cohort

(N=336 with TB, 362 without TB)

90.5

(86.8, 93.4)

98.1

(96.1, 99.2)

90.9

(87.1, 93.9)

98.7

(96.6, 99.6)

85.7

(67.3, 96)

95

(86.1, 99)

HIV-negative (N=222 with TB, 212 without TB)

90.8

(86.3, 94.1)

98.8

(96.5, 99.8)

91.4

(87.0, 94.8)

99.5

(97.4, 100)

81.3

(54.4, 96)

94.6

(81.8, 99.3)

HIV-positive

(N=86 with TB,

90 without TB)

89.8

(82.0, 95.0)

96.5

(91.2, 99.0)

89.5

(81.1, 95.1)

96.7

(90.6, 99.3)

91.7

(61.5, 99.8)

95.7

(78.1, 99.9)

CD4 < 100

(N=25 with TB,

15 without TB)

96.2

(80.4, 99.9)

95.0

(75.1, 99.9)

96.0

(79.6, 99.9)

93.3

(68.1, 99.8)

100

(2.5, 100)

100

(47.8, 100)

CD4 ≥100

(N=61 with TB,

75 without TB)

87.5

(77.6, 94.1)

96.8

(90.9, 99.3)

86.9

(75.8, 94.2)

97.3

(90.7, 99.7)

90.9

(58.7, 99.8)

94.4

(72.7, 99.9)