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Table 7 Influenza Diagnostic Algorithm Performance Including the following Symptoms: Fever> = 38 °C + Cough + Nasal discharge

From: Performance of case definitions and clinical predictors for influenza surveillance among patients followed in a rural cohort in Senegal

Case definition Sensitivity Specificity PPV* NPV P-values
Fever >=38°+ Cough + Nasal discharge % (95% CI) % (95% CI) % (95% CI) % (95% CI)  
All cases (n=1653) 65.0 (60.0–70.0) 72.0 (69.5–74.4) 40.0 (36.1–40.0) 88.2 (86.2–90.1) < 0.0001
Age groups (years)
 0 - <  2 59.1 (44.6–73.6) 60.0 (54.0–66.0) 20.0 (13.1–27.0) 89.5 (85.0–94.1) < 0.01
 2 - <  5 69.2 (59.0–79.4) 60.6 (55.0–66.4) 33.1 (26.0–40.3) 87.5 (83.0–92.2) < 0.001
 5 - <  15 69.0 (61.0–77.0) 77.5 (73.6–81.5) 48.0 (41.0–55.2) 89.3 (86.2–92.4) < 0.001
 15 - < 50 56.5 (46.0–67.0) 84.3 (80.1–88.6) 52.2 (42.0–62.4) 87.0 (82.5–90.5) < 0.001
 ≥ 50 71.4 (52.1–91.0) 81.2 (70.1–92.2) 62.5 (43.1–82.0) 87.0 (77.2–97.0) 0.16
  1. PPV* Positive Predictive Value, NPV Negative Predictive Value