Skip to main content

Table 3 Vaccine effectiveness of PPV23 in adults ≥75 years, estimated by the screening method, July 2008 to June 2016

From: Application of the screening and indirect cohort methods to evaluate the effectiveness of pneumococcal vaccination program in adults 75 years and older in Taiwan

IPD

VE

(95% CI)

All serotypes

 Crude VE

32.4%

(23.6 to 40.2)

 Adjusted by gender

33.2%

(24.4 to 40.9)

 Adjusted by age and gender

33.9%

(25.2 to 41.5)

Death within 30 days of IPD onset

 Crude VE

29.9%

(14.4 to 42.6)

 Adjusted by gender

30.8%

(15.5 to 43.4)

 Adjusted by age and gender

32.5%

(17.5 to 44.7)

PPV23 VT

 Crude VE

42.2%

(33.0 to 50.2)

 Adjusted by gender

42.9%

(33.8 to 50.7)

 Adjusted by age and gender

43.4%

(34.4 to 51.2)

PPV23-non PCV13 VT

 Crude VE

71.8%

(50.0 to 84.2)

 Adjusted by gender

72.1%

(50.5 to 84.3)

 Adjusted by age and gender

72.6%

(51.4 to 84.6)

PCV13 (without 6A) VT

 Crude VE

38.4%

(28.1 to 47.1)

 Adjusted by gender

39.1%

(29.0 to 47.8)

 Adjusted by age and gender

39.6%

(29.5 to 48.2)

  1. IPD invasive pneumococcal disease, VE vaccine effectiveness, CI confidence interval, VT vaccine type, PPV23 23-valent pneumococcal polysaccharide vaccine, PCV13 thirteen-valent pneumococcal conjugate vaccine, PPV23-non PCV13 VT 11 serotypes that included in PPV23 but not in PCV13, that is serotypes of 2, 8, 9 N, 10A, 11A, 12F, 15B, 17F, 20, 22F, and 33F