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Table 2 Comparison of treatment responses and clinical outcomes of patients infected with SARS-CoV-2 between non-severe and severe group

From: Risk factors and clinical features of deterioration in COVID-19 patients in Zhejiang, China: a single-centre, retrospective study

Variable

Total (N = 100)

Non-Severity (n = 51)

Severity (n = 49)

P Value

Treatments n (%)

    

Antivirus treatment

100 (100)

51 (100)

49 (100)

 

median (IQR), days

    

Time from illness onset to Antivirus start

7 (4–9.5)

6 (3–9)

7 (5–10)

0.2948

Glucocorticoid treatment n (%)

81 (81)

33 (64.7)

48 (98)

< 0.0001

Maximum dosage

80 (20–80)

80 (0–40)

80 (40–80)

0.0001

(equivalent methylprednisolone), median (IQR), mg/d

    

Artificial liver support n (%)

9 (9)

1 (2)

8 (16.3)

0.0148

Antibiotic treatment n (%)

24 (24)

2 (3.9)

22 (44.9)

< 0.0001

Oxygen support

   

< 0.0001

 Nasal cannular

64 (64)

46 (90.2)

18 (36.7)

 

 high-flow nasal cannula

13 (13)

3 (5.9)

10 (20.4)

 

 Invasive mechanical ventilation

23 (23)

2 (3.9)

21 (42.9)

 

median (IQR), days

ΑAT to first virologic conversion

9 (5–14)

6 (4–12)

9 (7–15)

0.0142

 AT to stable virologic conversion

10 (6–15)

7 (4–13)

12 (9–18)

0.0006

 AT to radiologic recovery

7 (4–10)

7 (5–11)

6.5 (4–9.5)

0.3162

 AT to temperature recovery

5 (2–8)

3 (2–7)

6.5 (2–9)

0.0903

Clinical outcomes, n (%)

 Discharge from hospital

86 (86)

49 (96.1)

37 (75.5)

0.0030

ΒICU admission

23 (23)

2 (3.9)

21 (42.9)

< 0.0001

 Death

0

0

0

0

  1. Abbreviation: ΑAT Antiviral therapy onset, ΒICU Intensive care unit